OBJECTIVE To analyse the use and development trend of Proton Pump Inhibitors(PPIs)in a hos-pital of Zhangzhou from 2020 to 2022,so as to provide reference for clinical rational use of drugs.METHODS The consumption sum,defined daily doses(DDDs),defined daily cost(DDC),and drug sequence ratio(B/A)in our hospital from 2020 to 2022 were analyzed statistically.RESULTS The overall consumption sum of PPIs showed a downward trend year by year.DDDs of Pantoprazole sodium enteric-coated tablets,Omeprazole eenteric-coated cap-sules and Rabeprazole sodium enteric-coated tablets were in the top three places.In three consecutive years,DDC of Eprazole enteric coated tablets for three consecutive years was the highest,while B/A was the lowest.Meanwhile,Omeprazole enteric coated capsules had the lowest DDC,with both B/A greater than 1.CONCLUSION The clini-cal use of PPIs in our hospital is basically reasonable,but efficacy and cost should be taken into account,while the clinical management and application of PPIs should be standardized and improved.
关键词
质子泵抑制剂/用药金额/用药频度/限定日费用/排序比
Key words
Proton pump inhibitors/Consumption sum/Frequency of drug use/Defined daily dose/Drug sequence ratio