A 74-year-old male patient with urinary tract infection and fever was treated with ceftazidime 2 g,ivd,q12h combined with ciprofloxacin 0.4 g,ivd,q12h for anti-infective treatment.Pancytopenia occurred 2 days later,the patient's clinical symptoms improved and body temperature retumed to normal,but pancyopenia appeared.The blood routine report was critical:WBC 1.49 × 109/L,RBC 2.67 × 1012/L,PLT 97 × 109/L,NEU 0.57 × 109/L,NEU％38.2％.Urine routine:leukocyte 2+,remaining normal;hs-CRP 48.30 mg·L-1;PCT 8.72 ng·mL-1.Considering the ADR caused by ceftazidine combined with ciprofloxacin,after stopping the two drugs,the patient was given a single dose of human granulocyte colony stimulating factor injection(75 μg ih)to support leukocytosis.After 12 days,the patient's pancytopenia recovered.
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