Analysis of Heavy Metal Elements in ShenLing BaiZhu Pills Based on ICP-MS and Health Risk Assessment
OBJECTIVE To analyze five heavy metal elements in ShenLing BaiZhu Pills and evaluate their health risks.METHODS Thirty six batches of ShenLing BaiZhu Pills were digested by microwave,and the contents of five elements(Pb,Cd,As,Hg,Cu)were determined by ICP-MS.The health risks of heavy metals and harmful ele-ments in ShenLing BaiZhu Pills were assessed by target hazard index combined with theoretical limit values and health guidance values.RESULTS The linear relationship between the elements was good,and the average recovery rate was between 90.2%and 101.0%.The RSD values of precision and repeatability were both less than 3%.Out of 36 batches of samples,5 batches of Hg elements exceeded the standard,all from the same enterprise,resulting in THQ values greater than 1.CONCLUSION This method is accurate,stable,and has good repeatability,and can be used for quality control of ShenLing BaiZhu Pills.This health risk assessment model can be applied to risk assessment of ShenLing BaiZhu Pills.
ShenLing BaiZhu PillHeavy metals and harmful elementsTarget hazardsRisk assessmentLimited quantity standard