海峡药学2024,Vol.36Issue(3) :33-38.

中药材二氧化硫残留量快速检测方法及其适用性比较

Comparison of Different Detection Methods of Sulfur Dioxide in Chinese Medicinal Herbs and their Applicability

杨一帆 李孟璇 刘文君 曹亮 王振中
海峡药学2024,Vol.36Issue(3) :33-38.

中药材二氧化硫残留量快速检测方法及其适用性比较

Comparison of Different Detection Methods of Sulfur Dioxide in Chinese Medicinal Herbs and their Applicability

杨一帆 1李孟璇 1刘文君 1曹亮 1王振中1
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作者信息

  • 1. 中药制药过程控制与智能制造技术全国重点实验室,江苏连云港 222001;江苏康缘药业股份有限公司,江苏连云港 222001
  • 折叠

摘要

目的 试验两种二氧化硫含量的快速检测方法并比较其适用性.方法 考查了凯氏定氮仪+滴定法和快速检测试剂盒对中药材中二氧化硫检测结果的准确度和可行性.结果 凯氏定氮仪+滴定法测定结果与2020 版《中国药典》中二氧化硫含量方法测定结果基本一致.结论 凯氏定氮仪+滴定法测定法,结果准确,可用于部分中药材的二氧化硫残留量检测,具有简便、快速、准确等特点,而快速检测试剂盒的检测结果适用比例较低.

Abstract

OBJECTIVE To test two rapid method for determination of sulfur dioxide residue in Chinese medic-inal herbs and compare their applicability.METHODS Examine the accuracy and feasibility of Kjeldahl Nitrogen Analyzer and rapid detection kit for determination of sulfur dioxide in Chinese medicinal herbs.RESULTS The re-sults of sample determination were basically consistent with those of Chinese pharmacopoeia(2020 edition).CONCLUSION The results of Kjeldahl nitrometer titration are accurate,and can be used to detect sulfur dioxide residues in some Chinese medicinal materials.It has the characteristics of simple,rapid and accurate.However,the application ratio of the test results of the rapid detection kit is low.

关键词

二氧化硫/快速检测方法/凯氏定氮仪/快速检测试剂盒

Key words

Sulfur dioxide/Rapid detection method/Kjeldahl Nitrogen Analyzer/Rapid Detection Kit

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基金项目

连云港市揭榜挂帅项目(CGJBGS2101)

出版年

2024
海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
参考文献量18
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