Coenzyme Q10 is an important electron carrier and antioxidant component of mitochondrial respiratory chain.It widely exists in human cells and has many functions.Its lack is closely related to many diseases.This paper reviews the main detection methods of coenzyme Q10 in drugs,dietary supplements and biological samples in recent years.Including the extraction and sample preparation of coenzyme Q10,the main determination methods such as HPLC-UV,HPLC-MS/MS,HPLC-ECD,HPLC-FL,HPLC-CL,spectrophotometry,fluorescence,electrochemical detec-tion,etc.In addition,the simultaneous determination of oxidized and reduced coenzyme Q10 was introduced,and the characteristics and applications of various analysis methods were summarized.
关键词
辅酶Q10/提取和样品制备/主要测定方法/研究进展
Key words
Coenzyme Q10/Extraction and sample preparation/Main determination methods/Research progress
维普
万方数据