Analysis of Detection Distribution and Drug Resistance of Escherichia coli in Clinical Departments from 2018 to 2022
OBJECTIVE To investigate the distribution and drug resistance of Escherichia coli in clinical sam-ples in recent 5 years,and to provide reference for rational selection of antibiotics in clinic.METHODS VITEK-COMPCAT bacterial identification and drug sensitivity analyzer was used to perform bacterial isolation and identifica-tion and drug sensitivity test on 9095 microbial samples(positive samples)submitted by clinical departments of the hospital from January 2018 to December 2022,and extended-spectrum β-lactamases(ESBLs)were detec-ted.Statistical analysis was performed in combination with relevant clinical information.RESULTS A total of 2073 strains of Escherichia coli were detected in all specimens,and the detection rate of Escherichia coli was 22.79%(2073/9095).A total of 701 strains of Escherichia coli produced ESBLs,and the enzyme production rate was 33.80%(701/2073).Among the submitted specimens,the highest proportion of Escherichia coli was detected in u-rine specimens(34.15%,708/2073).Among the clinical departments submitted for inspection,the highest propor-tion of Escherichia coli was 32.66%(677/2073)in gastrointestinal surgery.The sensitivity rates of meropenem,tige-cycline,amikacin,cefotetan and piperacillin/tazobactam were 100.00%,100.00%,98.87%,98.11%and 96.44%,respectively.CONCLUSION The detection rate of Escherichia coli increased first and then decreased steadily in the past five years.The proportion of Escherichia coli producing ESBLs showed a downward trend.Commonly used antibiotics maintained a high sensitivity rate to Escherichia coli.
万方数据
维普
