海峡药学2024,Vol.36Issue(5) :43-45.

滴定法测定娃娃宁散剂中朱砂的含量

Determination of Cinnabaris in WaWaNing by Titration

王凌波 刘云飞
海峡药学2024,Vol.36Issue(5) :43-45.

滴定法测定娃娃宁散剂中朱砂的含量

Determination of Cinnabaris in WaWaNing by Titration

王凌波 1刘云飞1
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作者信息

  • 1. 正大天晴药业集团股份有限公司,南京 211100
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摘要

目的 建立娃娃宁散剂中朱砂的含量测定方法.方法 首先优化硫酸和硝酸钾的比例,考察了方法的专属性、准确度、精密度、线性和稳定性,测定了9 批样品中的朱砂含量.结果 建立的方法准确度和精密度良好,平均回收率为94.4%(RSD=0.9%),其他药味对测定无干扰.结论 所建立的方法均符合要求,可作为娃娃宁质量控制的方法.

Abstract

OBJECTIVE To develop a method for determination content of cinnabaris in WaWaNing.METHODS The amount of concentrated sulfuric acid and nitrate of potash was optimized.Specificity,precision,ac-curacy,linearity and stability were investigated.The content of cinnabaris of nine batches of samples was deter-mined.RESULTS The detection method have good specificity,precision and high recovery.The average recovery was 94.4%(RSD=0.9%).CONCLUSION The method has been validated and could be applied to the quality control of WaWaNing.

关键词

娃娃宁/朱砂/含量测定/滴定

Key words

WaWaNing/Cinnabaris/Assay/Titration

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出版年

2024
海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
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