首页|我院注射用帕瑞昔布钠临床应用的干预效果分析

我院注射用帕瑞昔布钠临床应用的干预效果分析

扫码查看
目的 探讨多部门联合监督管理对我院注射用帕瑞昔布钠临床使用的综合干预效果,促进临床合理用药.方法 药学部门联合医务部、质控部等部门,制定本院注射用帕瑞昔布钠评价标准,建立药学干预与职能部门监督管理互相配合的干预模式.选取2021 年1~10 月(干预前)及2021 年11 月~2022 年8 月(干预后)使用注射用帕瑞昔布钠的住院患者病历127 份,回顾性分析干预前和干预后注射用帕瑞昔布钠的临床使用情况及合理用药情况.结果 干预前注射用帕瑞昔布钠的用药不合理率为70.00%,主要表现为给药疗程不合理,适应证不合理和禁忌证给药;干预后注射用帕瑞昔布钠的用药不合理率为29.85%,明显下降,主要表现在给药疗程不合理,但超疗程用药天数明显下降,P<0.05,有统计学意义.干预后注射用帕瑞昔布钠临床使用量较干预前明显下降,重点科室使用数量也明显下降.结论 多部门联合干预注射用帕瑞昔布钠的临床使用,降低了用药不合理率,降低了药品临床使用量,这一干预模式可推广应用到其他药品临床使用的管理.
Intervention Effect Analysis of Clinical Application of Parecoxib Sodium for Injection in One Hospital
OBJECTIVE To explore the comprehensive intervention effect of multi-department joint supervision and management on the clinical use of parecoxib sodium for injection in our hospital,so as to promote clinical rational drug use.METHODS The pharmacy department,together with the medical department,the quality control depart-ment and other departments,formulated the evaluation standard of parecoxib sodium for injection in our hospital,and formed an intervention model combining administrative supervision and management with pharmaceutical interven-tion.A total of 127 medical records of inpatients who used parecoxib sodium for injection from January to October 2021(before the intervention)and from November 2021 to August 2022(after the intervention)were selected.The clinical use and rational drug use of parecoxib sodium for injection before and after intervention were retrospectively analyzed.RESULTS Before the intervention,the irrational rate of parecoxib sodium for injection was 70.00%,which was mainly manifested as unreasonable course of administration,unreasonable indications and contraindications for administration.After the intervention,the irrational rate of parecoxib sodium for injection was 29.85%,which was significantly decreased,mainly due to the unreasonable duration of administration,but the number of days of overdose medication was significantly decreased,and the differences were statistically significant(P<0.05).After the inter-vention,the clinical use of parecoxib sodium for injection decreased significantly before the intervention,and the use in key departments also decreased significantly.CONCLUSION Multi-department joint intervention on the clinical use of parecoxib sodium for injection reduces the irrational rate of drug use and the clinical use of drugs.This inter-vention model can be extended and applied to the management of clinical use of other drugs.

Multi-sectorIntervention measuresParecoxib sodium for injectionRational drug use

汪国玉、黄玲玲、朱文靖、陈美玲、冯晓俊、王君萍

展开 >

中国科学院合肥肿瘤医院,安徽合肥 230022

中国科技大学附属第一医院/安徽省立医院,安徽合肥 230002

多部门 干预措施 注射用帕瑞昔布钠 合理用药

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(5)