Application of Dexmedetomidine Combined with Ropivacaine in Ultra-sound-guided Quadratus lumborum Block for Combined Analgesia after Cesarean Section
OBJECTIVE To investigate the feasibility and effectiveness of dexmedetomidine combined with rop-ivacaine in ultrasound-guided quadratus lumborum block for combined analgesia after cesarean section,and to provide reference for clinical selection of safe and effective analgesia.METHODS A total of 80 full-term parturients(ASAⅠ-Ⅱ)who planned to undergo cesarean section under combined epidural anesthesia were randomly divided into two groups by random table method:Control group(Group C)and Observation group(Group T),with 40 cases in each group.After operation,Group C was treated with PCIA.But Group T was treated with dexmedetomidine combined with ropivacaine in ultrasound-guided quadratus lumborum block followed by PCIA.The VAS scores at 4 h,8 h,12 h,24 h and 48 h after the operation were observed and compared between the two groups,as well as the number of PCA com-pression,flurbiprofen exate remedial dose,the occurrence of adverse reactions and the scores of patients′ satisfaction with analgesia within 48 h after the operation.RESULTS Compared with Group C,the VAS score of Group T was significantly decreased at 4 h,8 h,12 h,24 h and 48 h after the operation(P<0.05),the number of PCA compres-sion and flurbiprofen exate remedial dose were significantly decreased(P<0.05),and the incidence of adverse re-actions was significantly decreased(P<0.05),the analgesic satisfaction scores were significantly increased(P<0.05)within 48 h after the operation.CONCLUSION Dexmedetomidine combined with ropivacaine in ultrasound-guided quadratus lumborum block for combined analgesia after cesarean section can be safely and effectively,and it has certain application and promotion value in clinic.
万方数据
维普
