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关节置换围手术期抗凝药物使用评价和分析

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目的 对在我院关节外科接受关节置换手术治疗的患者围手术期抗凝药物使用情况进行评价和分析,为骨科合理使用抗凝药物提供参考.方法 采用回顾性研究的方法,通过检索我院合理用药监测系统,随机抽取2022 年1~12 月在我院关节一科和关节二科接受关节置换手术治疗的患者各300 例,依据药品说明书及相关指南文献等对其临床应用合理性进行评价.结果 院内抗凝药物的使用关节一科有33 例不合理(其中阿司匹林超说明书用药21 例),关节二科有40 例不合理(其中阿司匹林超说明书用药38 例);出院带药抗凝药物的使用关节一科有30例不合理(其中阿司匹林超说明书用药24 例),关节二科有262 例不合理(其中阿司匹林超说明书用药 254 例).结论 我院关节外科在抗凝药物合理使用方面还有较大的提升空间,骨科抗凝药物管理需要持续改进.
Evaluation and Analysis of Anticoagulant Drugs Use in Perioperative Peri-od of Joint Replacement
OBJECTIVE To evaluate and analyze anticoagulant drugs used in patients undergoing joint replace-ment surgery in our hospital to provide reference for rational drug use of anticoagulant drugs in orthope-dics.METHODS Using PASS system,the patients received joint replacement from January to December 2022 were selected for each 300 cases in two joint surgical departments,and were retrospectively analyzed according to the drug instructions and guidelines.RESULTS For inpatient medical orders,there were 33 cases(21 cases of off-label use of aspirin)and 40 cases(38 cases of off-label use of aspirin)of irrational use of anticoagulant drugs in the first and second joint surgical department respectively.For discharge medical orders,there were 30 cases(24 cases of off-label use of aspirin)and 262 cases(254 cases of off-label use of aspirin)of irrational use of anticoagulant drugs in the first and second joint surgical department respectively.CONCLUSION The joint surgical departments of our hospi-tal has still significant opportunities for enhancement in the rational use of anticoagulant drugs.The management of anticoagulant drugs in orthopedics needs continuous improvement.

Orthopedic surgeryJoint replacementAnticoagulant drugsdeep venous thrombosisRational drug use

陈泉金、魏小娟、徐冬闽

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福州市第二医院药学部,福建福州 350007

福建医科大学附属协和医院骨科,福建福州 350001

骨科 关节置换 抗凝药物 深静脉血栓 合理用药

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(5)