OBJECTIVE To optimize and establish the best preparation process of YanYan pills.METHODS According to the dissolving time limit of YanYan pills as measure index,the orthogonal test was employed to test the effects of the four factors,including crushing degree of medicinal materials(A),rounding time(B),drying tem-perature(C)and drying time(D).RESULTS The best forming technology of YanYan pills was as follows:medic-inal materials were crushed into 150 mesh powder,the pellets were rounded for 10 minutes,then the pills were made in drying at 70 ℃ for 14 h,respectively.CONCLUSION The optimized forming technology is stable with good re-producibility and the pills are round and smooth with uniform color,and the dissolving limit is short.The study pro-vides a suitable preparation process for industrial production.
关键词
咽炎丸/正交试验/工艺优化/溶散时限/水丸/塑制法
Key words
YanYan pills/orthogonal test/Optimization of process/Dissolving time limit/Watered pills/Molding method