首页|碳酸氢钠林格注射液制备工艺及包装系统研究

碳酸氢钠林格注射液制备工艺及包装系统研究

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目的 通过试验确定碳酸氢钠林格注射液的处方、工艺参数和包装系统.方法 对枸橼酸用量、工艺中的pH条件、灭菌条件、包装系统等进行筛选.结果 按照筛选出的处方、工艺参数、包装系统,可生产出符合质量标准的产品.结论 按确定的处方工艺生产碳酸氢钠林格注射液,工艺稳定,便于操作,产品质量安全、可控.
Study on the Preparation Process and Packaging System of Sodium Bi-carbonate Ringer's Injection
OBJECTIVE To determine the prescription,process parameters and packaging system of sodium bi-casbonate Ringer's injection through experiments.METHODS The dosage of citric acid,pH conditions in the process,sterilization conditions and packaging system were screened.RESULTS According to the selected prescrip-tion,process parameters and packaging system,the products meeting the quality standards can be pro-duced.CONCLUSION The production of sodium bicarbonate Ringer's injection according to the determined pre-scription process is stable,easy to operate,and the product quality is safe and controllable.

Sodium bicarbonateRingerInjectionPrescriptionWorkmanship

魏春燕、徐凡、张雯雯、刘任

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江苏正大丰海制药有限公司,江苏盐城 224100

碳酸氢钠 林格 注射液 处方 工艺

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(8)