海峡药学2024,Vol.36Issue(8) :3-6.

碳酸氢钠林格注射液制备工艺及包装系统研究

Study on the Preparation Process and Packaging System of Sodium Bi-carbonate Ringer's Injection

魏春燕 徐凡 张雯雯 刘任
海峡药学2024,Vol.36Issue(8) :3-6.

碳酸氢钠林格注射液制备工艺及包装系统研究

Study on the Preparation Process and Packaging System of Sodium Bi-carbonate Ringer's Injection

魏春燕 1徐凡 1张雯雯 1刘任1
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作者信息

  • 1. 江苏正大丰海制药有限公司,江苏盐城 224100
  • 折叠

摘要

目的 通过试验确定碳酸氢钠林格注射液的处方、工艺参数和包装系统.方法 对枸橼酸用量、工艺中的pH条件、灭菌条件、包装系统等进行筛选.结果 按照筛选出的处方、工艺参数、包装系统,可生产出符合质量标准的产品.结论 按确定的处方工艺生产碳酸氢钠林格注射液,工艺稳定,便于操作,产品质量安全、可控.

Abstract

OBJECTIVE To determine the prescription,process parameters and packaging system of sodium bi-casbonate Ringer's injection through experiments.METHODS The dosage of citric acid,pH conditions in the process,sterilization conditions and packaging system were screened.RESULTS According to the selected prescrip-tion,process parameters and packaging system,the products meeting the quality standards can be pro-duced.CONCLUSION The production of sodium bicarbonate Ringer's injection according to the determined pre-scription process is stable,easy to operate,and the product quality is safe and controllable.

关键词

碳酸氢钠/林格/注射液/处方/工艺

Key words

Sodium bicarbonate/Ringer/Injection/Prescription/Workmanship

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出版年

2024
海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
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