Predictive Analysis on Quality Markers(Q-Marker)of ZeXie Decoction Based on"Five Principles"
ZeXie decoction is a traditional Chinese medicine prescription,composed of two herbs:ZeXie and BaiZhu,which can be used to promote diuresis and eliminate fluid retention,and invigorating the spleen to make wa-ter.It has pharmacological effects such as diuresis,anti calculi,kidney and liver protection,lowering blood lipids,low-ering blood sugar,and anti-inflammatory.And the clinical studies have also showed ZeXie decoction was effective for the treatment of hypertension,hyperlipidemia,dizziness,and cerebral blood supply deficiency,etc.Based on litera-tures and guided by traditional Chinese medicine theory,this article predicts and analyzes the quality markers(Q-markers)of ZeXie decoction from five principles:quality transmission and traceability,component specificity,correla-tion between components and effectiveness,compound compatibility environment,and component measurability,in or-der to provide reference basis for the quality control research of ZeXie decoction.
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