海峡药学2024,Vol.36Issue(8) :94-96.

动脉粥样硬化性心血管疾病(ASCVD)的下一个管理靶点——抗炎治疗

The Next Management Target of ASCVD-anti-inflammatory therapy

李丽鹃
海峡药学2024,Vol.36Issue(8) :94-96.

动脉粥样硬化性心血管疾病(ASCVD)的下一个管理靶点——抗炎治疗

The Next Management Target of ASCVD-anti-inflammatory therapy

李丽鹃1
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作者信息

  • 1. 晋江市第二医院,福建泉州 362261
  • 折叠

摘要

既往认为胆固醇是动脉粥样硬化性心血管疾病(ASCVD)的致病危险因素,随着研究的深入,ASCVD不再被认为是单纯的动脉壁脂质堆积疾病,而可能是一种进展性炎症反应.本文通过回顾冠状动脉抗炎策略的发展,明确了"炎症学说",复习小剂量秋水仙碱在冠心病应用的几个研究,进一步明确炎症治疗将为ASCVD的下一个管理靶点,管理炎症对降低心血管风险事件具有重要意义.

Abstract

In the past,cholesterol was believed to be a pathogenic risk factor for ASCVD.With the deepening of research,ASCVD is no longer considered a simple arterial wall lipid accumulation disease,but may be a progressive inflammatory response.This article reviews the development of coronary artery anti-inflammatory strategies,clarifies the"inflammation theory",reviews several studies on the application of low-dose colchicine in coronary heart dis-ease,and further clarifies that inflammation treatment will be the next management target of ASCVD.Managing in-flammation is of great significance in reducing cardiovascular risk events.

关键词

炎症/减少炎症/秋水仙碱/C反应蛋白/ASCVD管理靶点

Key words

Inflammation/Reduce inflammation/Colchicine/C-reactive protein/ASCVD management targets

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出版年

2024
海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
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