Monitoring of Adverse Reactions of Bevacizumab by Clinical Pharmacists in Our Hospital
OBJECTIVE The Adverse reactions(ADR)of bevacizumab in our hospital were monitored and an-alyzed to promote the safety of medication.METHODS Clinical pharmacists actively monitored 173 cancer patients who were treated with bevacizumab and developed ADR in our hospital from January 1,2022 to August 31,2023,and analyzed the occurrence and characteristics of ADR.RESULTS Among the 83 patients,48 were males(57.83％)and 35 were females(42.17％).53.01％of patients aged 65-74 years;ADR mainly occurred in the blood system and gastrointestinal system,among which the incidence of leukopenia(15.03％),bone marrow suppression(16.76％),gastrointestinal reaction(16.76％)and hypertension(7.51％)were higher.ADR occurred within 30 days(83.82％).The combination of two drugs(66.47％)was the most common treatment regimen.130 cases im-proved after treatment.CONCLUSION Clinical monitoring of drug ADR should be strengthened to improve the ra-tionality and safety of drug use and reduce the occurrence of ADR.
Adverse drug reactionsBevacizumabRational drug usePharmaceutical care
万方数据
维普
