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近5年国家谈判的抗肿瘤药纳入医保的品种及适应症变化分析

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目的 统计2019年到2023年五版国家医保目录协议期内谈判的抗肿瘤药品种的变化及医保限定的支付病种范围的变更,重点对单克隆抗体和蛋白激酶抑制剂的部分特殊品种的适应症变化进行分析。方法 以表格的形式罗列出五版国家医保目录协议期内谈判的各类抗肿瘤药的品种个数、纳入年份及医保限定的支付病种范围。结果 五版国家医保目录中协议期内谈判的抗肿瘤药的品种总数呈逐年递增趋势,各类抗肿瘤药的品种数排前3位的均是蛋白激酶抑制剂、单克隆抗体、其他类抗肿瘤药。医保限定的支付病种涵盖各个系统的肿瘤,如呼吸系统、消化系统、血液系统、泌尿系统、乳腺等,其中呼吸系统所占比例最高。部分品种连续5年均进入国家谈判药品目录。结论 传统的抗肿瘤药由于不良反应大,患者无法耐受,近年来已逐渐被新型抗肿瘤药所替代。但由于新型抗肿瘤药价格昂贵,患者又需要长时间使用,故需要国家干预,尽可能降低价格,方能满足肿瘤患者的用药需求和可及性,从而减轻经济负担,提高生活质量。
Analysis of the Varieties and Indications of Anti-tumor Drugs Included in the Medical Insurance in Recent 5 Years
OBJECTIVE To analyze the changes in the types of anti-tumor drugs negotiated during the five-year National Medical Insurance catalog agreement period from 2019 to 2023 and the changes in the scope of payment dis-eases limited by medical insurance,the indications of monoclonal antibodies and protein kinase inhibitors were ana-lyzed.MTEHODS In the form of a table,the number of anti-tumor drugs negotiated during the fifth edition of the National Medical Insurance catalogue agreement,the year of inclusion and the scope of payment limited by medical insurance were listed.RESULTS The total number of anti-tumor drugs negotiated during the agreement period in the fifth edition of the National Medical insurance catalog showed an increasing trend year by year,and the top 3 types of anti-tumor drugs were protein kinase inhibitors,monoclonal antibodies and other anti-tumor drugs.The pay-ment diseases limited by the medical insurance cover tumors of various systems,such as respiratory system,digestive system,blood system,urinary system,mammary gland,etc.,of which the respiratory system accounts for the highest proportion.Some varieties entered the national negotiation drug list for five consecutive years.CONCLUSION Tra-ditional anti-tumor drugs have been gradually replaced by new anti-tumor drugs in recent years due to their adverse reactions.However,due to the high price of new anti-tumor drugs and the long-term use of patients,national interven-tion is needed to reduce the price as much as possible to meet the drug needs and accessibility of cancer patients,so as to reduce the economic burden and improve the quality of life.

National medical insurance directoryNegotiate drugs during the agreement periodAntitumor agentsProtein kinase inhibitorsMonoclonal antibody

杨丽雄、蔡丽秋

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厦门大学附属第一医院药剂科,福建厦门 361003

厦门大学附属第一医院杏林分院药剂科,福建厦门 361102

国家医保目录 协议期内谈判药品 抗肿瘤药 蛋白激酶抑制剂 单克隆抗体

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(10)