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基于中药院内制剂研发建立中药临床药师工作新模式

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目的 阐述中药临床药师参与中药院内制剂研发各环节工作内容,探索中药临床药学工作新模式.方法 简述中药临床药学发展现状与工作模式,结合我院实践,阐述中药临床药师参与中药院内制剂研发各环节的工作内容和特色性.结果 中药临床药师可通过跟诊抄方、数据挖掘及文献整理等方式,协助临床挖掘有开发前景的处方;对待开发的中药院内制剂处方进行论证,包括命名、处方来源和化裁依据、组方和剂型创新性、明确临床定位及安全性等;基于医院HIS真实世界数据,开展中药院内制剂的安全性和有效性评价及作用机制研究,为推进院内制剂备案及向新药二次开发奠定基础.结论 各级别中医院对中药院内制剂开发有着迫切的需求,建立中药临床药师主导,医药共同参与的中药院内制剂研发团队十分必要和可行,符合中药临床药师深入临床和开展特色中药学服务的工作定位.
Establishment of a New Model for the Work of Chinese Medicine Clinical Pharmacists Based on the Research and Development of Chinese Medi-cine Hospital Preparations
OBJECTIVE To expound the work content of Chinese medicine clinical pharmacists participating in the research and development of Chinese medicine hospital preparations,and to explore a new mode of Chinese medi-cine clinical pharmacy.METHODS The development status and working mode of clinical pharmacy of traditional Chinese medicine were briefly described.Combined with the practice of our hospital,the work content and character-istics of clinical pharmacists participating in the preparation of traditional Chinese medicine were expoun-ded.RESULTS Clinical pharmacists of traditional Chinese medicine could assist in clinical mining of prescriptions with development prospects by means of follow-up,data mining and literature review.Clinical Pharmacists demonstra-ted the prescription of traditional Chinese medicine hospital preparations to be developed,including naming,prescrip-tion source and tailoring basis,innovative formulation and dosage form,clear clinical positioning and safety.Based on the real world data of hospital HIS,the safety and efficacy evaluation and mechanism of action of hospital preparations of traditional Chinese medicine were studied,which laid a foundation for promoting the filing of hospital preparations and the secondary development of new drugs.CONCLUSION Traditional Chinese Medicine hospitals at all levels have an urgent need for the development of hospital preparations of traditional Chinese medicine.It is necessary and feasible to establish a Traditional Chinese Medicine hospital preparation research and development team led by clini-cal pharmacists of traditional Chinese medicine and jointly participated by medicine,which is in line with the positio-ning of clinical pharmacists of traditional Chinese medicine to go deep into clinical practice and carry out characteris-tic Chinese pharmacy services.

Clinical pharmacy of traditional Chinese medicineWorking modeChinese medicine hospital preparations

张静、李文静、刘军

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银川市中医医院,宁夏银川 750000

中药临床药学 工作模式 中药院内制剂

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(11)