海峡药学2024,Vol.36Issue(11) :111-114.

1例头孢他啶致重度血小板减少患者的药学监护

Pharmaceutical Care of Severe Thrombocytopenia Possibly Caused by Ceftazidime:A Case Report

吴紫娟 王珂杰 金姿 蔡晓辉 王康
海峡药学2024,Vol.36Issue(11) :111-114.

1例头孢他啶致重度血小板减少患者的药学监护

Pharmaceutical Care of Severe Thrombocytopenia Possibly Caused by Ceftazidime:A Case Report

吴紫娟 1王珂杰 2金姿 3蔡晓辉 4王康1
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作者信息

  • 1. 常州市第二人民医院药学部,江苏常州 213100
  • 2. 陕西省中医药大学,陕西咸阳 712046
  • 3. 常州市武进区嘉泽卫生院药剂科,江苏常州 213152
  • 4. 常州市第二人民医院血液科,江苏常州 213100
  • 折叠

摘要

1例71岁女性,因"发现皮肤瘀斑、口腔出血、重度血小板减少"急诊入院.完善相关检验检查及骨髓穿刺,排除了引起血小板减少的常见原因.临床药师在药学监护时了解到患者近期有抗感染药物使用史,遂联系患者的家庭药师,调阅近期的就诊及用药记录,并进行循证分析,提出患者重度血小板减少可能与抗感染药物"头孢他啶"相关.治疗上予以丙种球蛋白、甲泼尼龙冲击治疗,联合使用促血小板生成素、输注血小板等升血小板治疗.5天后患者血小板恢复正常,顺利出院.

Abstract

One 71-year-old female Patient was admitted to the emergency department for"detected skin spots,o-ral bleeding and severe thrombocytopenia".Relevant tests and bone marrow puncture were improved to exclude the common causes of thrombocytopenia.The clinical pharmacist learned that the patient had a recent history of anti-in-fectious drugs,so he contacted the patient's family doctor to review the recent treatment and medication records,and conducted evidence-based analysis,suggesting that the patient's severe thrombocytopenia might be related to the anti-infectious drug"ceftazidime".On treatment,gamma globulin and methylprednisolone were treated,and ascending platelet treatment such as thrombopoietin and platelet transfusion were jointly used.Five days later,the patient re-turned to normal platelets and was discharged smoothly.

关键词

头孢他啶/血小板减少/药学监护/药物不良反应

Key words

Ceftazidime/Thrombopoietin/Pharmaceutical Care/Adverse Drug Reaction

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出版年

2024
海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
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