首页|1例头孢他啶致重度血小板减少患者的药学监护

1例头孢他啶致重度血小板减少患者的药学监护

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1例71岁女性,因"发现皮肤瘀斑、口腔出血、重度血小板减少"急诊入院。完善相关检验检查及骨髓穿刺,排除了引起血小板减少的常见原因。临床药师在药学监护时了解到患者近期有抗感染药物使用史,遂联系患者的家庭药师,调阅近期的就诊及用药记录,并进行循证分析,提出患者重度血小板减少可能与抗感染药物"头孢他啶"相关。治疗上予以丙种球蛋白、甲泼尼龙冲击治疗,联合使用促血小板生成素、输注血小板等升血小板治疗。5天后患者血小板恢复正常,顺利出院。
Pharmaceutical Care of Severe Thrombocytopenia Possibly Caused by Ceftazidime:A Case Report
One 71-year-old female Patient was admitted to the emergency department for"detected skin spots,o-ral bleeding and severe thrombocytopenia".Relevant tests and bone marrow puncture were improved to exclude the common causes of thrombocytopenia.The clinical pharmacist learned that the patient had a recent history of anti-in-fectious drugs,so he contacted the patient's family doctor to review the recent treatment and medication records,and conducted evidence-based analysis,suggesting that the patient's severe thrombocytopenia might be related to the anti-infectious drug"ceftazidime".On treatment,gamma globulin and methylprednisolone were treated,and ascending platelet treatment such as thrombopoietin and platelet transfusion were jointly used.Five days later,the patient re-turned to normal platelets and was discharged smoothly.

CeftazidimeThrombopoietinPharmaceutical CareAdverse Drug Reaction

吴紫娟、王珂杰、金姿、蔡晓辉、王康

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常州市第二人民医院药学部,江苏常州 213100

陕西省中医药大学,陕西咸阳 712046

常州市武进区嘉泽卫生院药剂科,江苏常州 213152

常州市第二人民医院血液科,江苏常州 213100

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头孢他啶 血小板减少 药学监护 药物不良反应

2024

海峡药学
中国药学会福建分会

海峡药学

影响因子:0.643
ISSN:1006-3765
年,卷(期):2024.36(11)