Effect of Metoprolol on Ventricular Arrhythmia and Cardiac Function in Elderly Patients with Hypertensive Heart Disease
Objective To investigate the therapeutic effect of metoprolol on ventricular arrhythmia in elderly patients with hypertensive heart disease and its effect on cardiac function.Methods A total of 120 elderly patients with hypertensive heart disease ventricular arrhythmia were randomly divided into control group and observation group,with 60 cases in each group.The control group was treated with irbesar-tan,and the observation group with metoprolol on the basis of the control group.The total effective rate,blood pressure,heart rate,QT dispersion and cardiac function of the two groups were observed.Results The total effective rate of the observation group was significantly higher than that of the control group(P＜0.05).After treatment,it decreased and the observation group decreased more significantly(P＜0.05).There was no statistically significant difference in systolic blood pressure,diastolic blood pres-sure,and heart rate between the two groups of patients before treatment(P＞0.05).After treatment,the QT dispersion index of the patients decreased and the observation group decreased more significantly(P＜0.05).There was no statistically significant difference in QTc and QTd between the two groups of patients before treatment(P＞0.05).After treatment,LVEF and CO increased,LVESD decreased,and the improvement in the observation group was better than that in the control group(P＜0.05).There was no significant difference in the incidence of adverse events such as hypotension between the two groups(P＞0.05).Conclusion Metoprolol can significantly improve the total effective rate of treatment in patients with hypertensive heart disease ventricular arrhythmia,effectively reduce blood pressure,re-store heart rate to normal range,improve QT dispersion,enhance cardiac function,and do not signifi-cantly increase the incidence of adverse events.
Old ageHypertensive heart diseaseVentricular arrhythmiaMetoprololCardiac function
万方数据
维普
