河北北方学院学报(自然科学版)2025,Vol.41Issue(2) :23-27.DOI:10.3969/j.issn.1673-1492.2025.02.006

半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化临床疗效分析

Therapeutic Efficacy of Banxia Baizhu Tianma Decoction in Addressing Type 2 Diabetes Mellitus Combined with Carotid Atherosclerosis

孙小明 翟江 杨庆华 赵贞
河北北方学院学报(自然科学版)2025,Vol.41Issue(2) :23-27.DOI:10.3969/j.issn.1673-1492.2025.02.006

半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化临床疗效分析

Therapeutic Efficacy of Banxia Baizhu Tianma Decoction in Addressing Type 2 Diabetes Mellitus Combined with Carotid Atherosclerosis

孙小明 1翟江 1杨庆华 1赵贞2
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作者信息

  • 1. 河北北方学院附属第二医院功能科,河北 张家口 075100
  • 2. 河北华奥医院超声科,河北 张家口 075000
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摘要

目的 探讨半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化的临床疗效.方法 98例2型糖尿病合并颈动脉粥样硬化患者按数字表法随机分为半夏白术天麻汤组及常规治疗组各49例,常规治疗组患者进行常规治疗,半夏白术天麻汤组患者在常规治疗基础上给予半夏白术天麻汤治疗.6个月为1疗程.结果 治疗1疗程后,半夏白术天麻汤组患者空腹血糖、餐后2h血糖及糖化血红蛋白水平均低于常规治疗组;总胆固醇、甘油三酯及低密度脂蛋白胆固醇水平低于常规治疗组,高密度脂蛋白胆固醇水平高于常规治疗组;颈动脉内膜中层厚度、斑块体积及斑块数量均低于常规治疗组.不良反应发生率组间比较差异无统计学意义.结论 在常规治疗基础上合用半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化可有效降低患者血糖、血脂水平,改善颈动脉斑块状况,且不明显增加不良反应.

Abstract

Objective To explore the therapeutic efficacy of Banxia Baizhu Tianma decoction in manag-ing type 2 diabetes mellitus coupled with carotid atherosclerosis.Methods A total of 98 patients with type 2 diabetes mellitus and carotid atherosclerosis were randomly and equally allocated into two groups:the Banxia Baizhu Tianma decoction group and the conventional treatment group.The conventional treat-ment group received standard medical therapy,whereas the Banxia Baizhu Tianma decoction group was ad-ministered Banxia Baizhu Tianma decoction alongside the conventional treatment.Six months are one course of treatment.Results Upon completion of the treatment regimen,patients in the Banxia Baizhu Tianma decoction group demonstrated significantly lower fasting blood glucose,2-hour postprandial blood glucose,and glycated hemoglobin levels in comparison with the conventional treatment group.Addition-ally,the levels of total cholesterol,triglyceride,and low-density lipoprotein were notably reduced in the Banxia Baizhu Tianma decoction group,while high-density lipoprotein levels were enhanced.The Banxia Baizhu Tianma decoction group exhibited diminished intima-media thickness,plaque volume,and plaque count in the carotid arteries relative to the conventional treatment group.No statistically significant dis-parity in the incidence of adverse reactions was observed between the two groups.Conclusion The inte-gration of Banxia Baizhu Tianma decoction in the therapeutic regimen for patients afflicted with type 2 dia-betes mellitus and carotid atherosclerosis substantively reduces blood glucose and lipid levels,ameliorates carotid plaque condition,and there is no significant increase in adverse reactions.

关键词

半夏白术天麻汤/2型糖尿病/颈动脉粥样硬化/血糖/血脂/颈动脉斑块

Key words

Banxia Baizhu Tianma decoction/Type 2 diabetes/Carotid atherosclerosis/Blood glu-cose/Blood lipid/Carotid plaque

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出版年

2025
河北北方学院学报(自然科学版)
河北北方学院

河北北方学院学报(自然科学版)

影响因子:0.348
ISSN:1673-1492
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