Determination of seven components in licorice and its different processed products by QAMS
In order to achieve the quality evaluation of multiple indicator components in licorice and its processed products,a quantitative analysis of multi-components by single marker(QAMS)was established to determine the content of seven chemical components in licorice medicinal materials and three different processed products.The calibration factor for isoliquiritigenin was calculated by using glycyrrhizin as the internal standard;The relative correction factors of apigenin glycyrrhizic acid,apigenin isoliquiritigenin,neoisoliquiritigenin,and glycyrrhizin were calculated by using glycyrrhetinic acid as the internal standard,and then the content of each component was determined.The calculated results were compared with the results obtained by the external standard method.The results show that the QAMS is feasible for determining the content of seven components in licorice and its different processed products.After processing,the content of glycyrrhizin,glycyrrhetinic acid,apigenin glycyrrhizin,apigenitigenin,and neoisoglycyrrhizin all decreases and shows the same trend of change.The trend of content change is ω(licorice herbs)＞co(fried licorice)＞ω(licorice tablets)＞ω(roasted licorice).The established method is stable,accurate,and has good repeatability,which can provide reference for the quality evaluation of licorice and its different processed products.
chemistry of Chinese materia medicalicoriceprocessed productsQAMSquality evaluation
万方数据
维普
