Research progress on the anti-inflammatory mechanism of WuTou Decoction in rheumatoid arthritis
Rheumatoid arthritis(RA)is a chronic systematic autoimmune disease with the main clinical and pathological characteristics of synovial inflammation and joint cartilage and bone destruc-tion.Inflammation,as the core pathological link and key prognostic link of RA,affects the develop-ment and outcome of the disease.If the synovial inflammation persists,it will ultimately lead to joint stiffness,deformation,bone destruction and functional loss.Wutou Decoction(WTD)can play the role of warming the channels,nourishing qi and dispelling cold and dampness,and is the basic pre-scription for the treatment of cold-damp arthralgia type RA.In this paper,the research methods of literature review are used to summarize the recent research on the anti-inflammatory mechanism of WTD.It is found that WTD can regulate inflammatory cytokines and inflammatory mediators by the synergistic effect of single drug anti-inflammatory active ingredients to play anti-inflammatory effect.
NETL
NSTL
万方数据
维普
