Value of an ultrasound multiparametric Z-score combined model to assess fetal growth restriction
Objective To investigate the value of the combined prediction model of ultrasound multi-parameter Z-score in assessing fetal growth restriction(FGR).Methods The clinical data of 88 pregnant women with single pregnancy,22-29 weeks of pregnancy,and FGR infants born after deliv-ery in our hospital from January 2017 to December 2020 were retrospectively analyzed.The general in-formation such as age,parity,pregnancy comorbidity was basically matched with that of 108 non-FGR pregnant women.The single parameter model and the multi-parameter combined model of fetal body mass measurement(EFW),umbilical artery(UA),middle cerebral artery(MCA),cerebral-placental ratio(CPR),abdominal circumference(AC)and head-abdominal circumference ratio(HC/AC)were established by using logistic regression equation.The receiver operating characteristic curve(ROC)was plotted,and the value of different models in predicting FGR was evaluated by comparing with Hadlock-EFW percentile(Hadlock-EFWc).Results The Z-scores of EFW,EFWc,CPR,AC and HC/AC in the FGR group were significantly lower than those in the non-FGR group,while the Z-scores of UA-PI and MCA-PI were higher than those in the non-FGR group(P＜0.001).The sensi-tivity,specificity,Youden index and area under the ROC curve(AUC)of the combined model for pre-dicting FGR were 82.95％,70.37％,0.533 and 0.897,respectively,with 95％CI of(0.795,0.956).Its predictive performance was better than that of Hadlock-EFWc and each single ultrasound parameter(P＜0.05).Conclusion The combined model of ultrasound multi-parameter Z-score is more accu-rate and has higher diagnostic value than Hadlock-EFWc and each single ultrasound parameter in pre-dicting FGR.
NETL
NSTL
万方数据
维普
