首页|泌尿系统术后留置双J管患者并发尿路感染列线图预测模型建立及验证

泌尿系统术后留置双J管患者并发尿路感染列线图预测模型建立及验证

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目的 通过建立泌尿系统术后留置双J 管患者尿路感染(UTI)临床预测模型,提高临床对于此类患者的诊治能力.方法 选择 2018 年 1 月~2022 年 7 月本院泌尿外科接受手术留置双J 管患者为研究对象,经病历筛选最终入组研究对象共 137 例,将尿路感染患者纳入 UTI 组,未发生尿路感染者纳入非UTI组.对性别、年龄、体质量指数(BMI)、双J 管留置时间、合并糖尿病、尿路感染史、术前营养控制状态评分(COUNT)、手术时间、双J 管侧别、合并肾功能不全情况进行统计,采用 R-studio 4.0.2软件的"RMS"函数包完成多因素Logistic回归模型建立、列线图绘制,模型及单因素对双J 管感染的诊断价值分析采用受试者工作特征曲线(ROC)进行评价.结果 UTI组与非 UTI 组性别、年龄、BMI、合并糖尿病、手术时间、双J 管侧别、合并肾功能情况比较差异无统计学意义(P>0.05),UTI 组双J 管留置时间、术前COUNT评分、尿路感染史比例均高于非UTI组(P<0.05);多因素Logistic回归分析结果发现双J 管留置时间、尿路感染史、术前COUNT评分均为泌尿系统术后留置双J 管相关尿路感染的独立影响因素(P<0.05),Bootstrap 法对预测模型列线图进行内部验证,Hosmer-Lemeshow检验结果显示χ2=6.753,P =0.325,说明模型具有良好的校准度;ROC分析结果显示,双J 管留置时间、尿路感染史、术前COUNT评分预测术后尿路感染的曲线下面积(AUC)分别为 0.793、0.747、0.750,3 个单因素联合建立的预测模型预测术后尿路感染的AUC为 0.925,均具有良好的预测效能(P<0.05).结论 基于双J 管留置时间、尿路感染史、术前COUNT评分所建立的预测模型对泌尿系统术后留置双J 管患者尿路感染的发生概率有较好的预测能力,可在早期识别尿路感染高风险人群.
Establishment and validation of nomographic prediction model for urinary tract infection in patients with double-J tube indwelling after urological surgery
Objective To establish a clinical prediction model of urinary tract infection(UTI)in patients with indwelling double J stents after urological surgery to improve the diagnosis and treatment of such patients.Methods A total of 137 patients who underwent urological surgery and indwelling double J stents in our hospital from January 2018 to July 2022 were selected as the research subjects.After medical record screening,a total of 137 subjects were included in the study,and patients with UTI were included in the UTI group,and those without UTI were included in the non-UTI group.The gender,age,body mass index(BMI),indwelling time of double J stents,diabetes mellitus,his-tory of urinary tract infection,preoperative nutritional status score(COUNT),operation time,side of double J stents,and combined renal dysfunction were collected.The multi-factor Logistic regression model was established using the"RMS"function package of R-studio 4.0.2 software,and the line chart was plotted.The diagnostic value of the model and single factors for double J stent infection was evalu-ated using the receiver operating characteristic curve(ROC).Results There were no significant differ-ences in gender,age,BMI,diabetes mellitus,operation time,side of double J stents,and combined renal dysfunction between the UTI group and the non-UTI group(P>0.05).The indwelling time of double J stents,preoperative COUNT score,and proportion of urinary tract infection history in the UTI group were higher than those in the non-UTI group(P<0.05).Multivariate Logistic regression analysis showed that the indwelling time of double J stents,urinary tract infection history,and preop-erative COUNT score were independent risk factors for postoperative urinary tract infection after uro-logical surgery with indwelling double J stents(P<0.05).The internal validation of the prediction model line chart was performed using the Bootstrap method.The Hosmer-Lemeshow test showed that χ2=6.753 and P =0.325,indicating that the model had good calibration.ROC analysis showed that the AUCs of double J stent indwelling time,urinary tract infection history,and preoperative COUNT score for predicting postoperative UTI were 0.793,0.747,and 0.750,respectively.The AUC of the prediction model established by these three individual factors for predicting postoperative UTI was 0.925,indicating good predictive accuracy(P<0.05).Conclusion The prediction model based on doub-le J stent indwelling time,urinary tract infection history,and preoperative COUNT score has good predictive ability for the occurrence probability of urinary tract infection in patients with indwelling double J stents after urological surgery,which can be used to identify high-risk groups of urinary tract infection in the early stage.

Urological surgeryDouble J stentUrinary tract infectionPrediction modelLine chart

吴利兵、曹勇、庒华、厉波、李超群

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日照市中心医院泌尿外科 山东日照 276800

泌尿系统手术 双J 尿路感染 预测模型 列线图

2024

华北理工大学学报(医学版)
河北联合大学

华北理工大学学报(医学版)

影响因子:0.569
ISSN:2095-2694
年,卷(期):2024.26(2)
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