Meta-analysis of the rehabilitation effect of tDCS combined with MT on upper limb function and activities of daily living in stroke patients
Objective To systematically evaluate the clinical efficacy of transcranial direct current stimulation(tDCS)combined with mirror therapy(MT)in the rehabilitation of upper limb function and activities of daily living in stroke patients.Methods A computer search of PubMed,Web of Sci-ence,The Cochrane library,Embase,CNKI,WanFang,VIP and the Chinese Biomedical Literature Database was conducted to collect all randomized controlled trials of tDCS combined with MT for the treatment of upper limb dysfunction in stroke patients.The search period was from the establishment of the database to January 2023.Two researchers independently extracted the data.Meta-analysis was performed using RevMan 5.4 software.The main outcome indicators were evaluated:Fugl-Meyer Up-per Limb Function Scale(FMA-UL)score and modified Barthel Index scale(MBI)score.Secondary outcome indicators:Boxes Block Test(BBT)score.Results A total of 7 randomized controlled trials were included,involving 379 patients.Meta-analysis showed that compared with the tDCS alone group,the combined group had significantly higher FMA-UL scores[MD=5.17,95%CI(3.80,6.54)]and MBI scores[MD=6.71,95%CI(4.61,8.80)].Compared with the MT alone group,the combined group had significantly higher FMA-UL scores[MD=6.72,95%CI(3.67,9.76)],MBI scores[MD=17.91,95%CI(2.49,33.33)]and BBT scores[MD=9.52,95%CI(3.30,15.74)].Con-clusion Compared with the use of tDCS or MT alone,tDCS combined with MT has a more significant effect in improving upper limb motor function and activities of daily living in stroke patients.
Transcranial direct current stimulationMirror therapyStrokeMeta-analysis
万方数据
维普
