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狼疮性肾炎的病因病机认识及中医辨治思路

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本文通过探讨狼疮性肾炎(LN)的中医病因病机及辨治用药规律,为诊治 LN 提供思路与方法.首先从先天禀赋、外感六淫、日晒毒、药毒及情志失调等方面探讨中医病因病机,并结合诊治 LN 的临床验案,分析辨治思路及用药特色.笔者认为LN病因复杂,本虚标实为其基本病机,标实以热毒、湿浊、血瘀为主,本虚以肝肾阴虚、气阴两虚、脾肾亏虚为主.运用中医药治疗 LN,不仅能够明显改善病情,同时能够减轻西药的不良反应,临床疗效显著.
Understanding of etiology and pathogenesis of lupus nephritis and the thinking of syndrome differentiation and treatment in traditional Chinese medicine
This article aims to provide ideas and methods for the diagnosis and treatment of lu-pus nephritis(LN)by exploring the etiology,pathogenesis,and medication rules of traditional Chi-nese medicine(TCM)in the treatment of LN.Firstly,the etiology and pathogenesis of LN are dis-cussed from the perspectives of innate endowment,external six evils,sun poisoning,drug poisoning,and emotional imbalance.Combined with clinical case studies on the diagnosis and treatment of LN,the thinking and medication characteristics of syndrome differentiation and treatment are analyzed.The author believes that the etiology of LN is complex,with deficiency in essence and excess in superficiali-ty as its basic pathogenesis.The excess in superficiality is mainly manifested as heat-toxicity,damp-turbidity,and blood stasis,while the deficiency in essence is mainly manifested as yin deficiency of liv-er and kidney,deficiency of qi and yin,and deficiency of spleen and kidney.The use of TCM in the treatment of LN can not only significantly improve the condition,but also reduce the adverse reactions of Western medicine,with remarkable clinical effects.

Lupus nephritisDiagnosis and treatment based on syndrome differentiationEtiolo-gy and pathogenesisTraditional Chinese medicineTreatment approach

祝昌昊、杨精华、王耀光、刘远航

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天津中医药大学第一附属医院肾病科 天津 300381

狼疮性肾炎 辨证论治 病因病机 中医药 治疗思路

国家重点研发计划全国名老中医药专家传承工作室建设项目王耀光天津市名中医传承工作室项目

2018YFC1704102978022883022

2024

10.19539/j.cnki.2095-2694.2024.02.012

华北理工大学学报(医学版)
河北联合大学

华北理工大学学报(医学版)

影响因子：0.569
ISSN：2095-2694
年,卷(期)：2024.26(2)
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