Objective To analyze the combined predictive value of serum procalcitonin(PCT)and sequential organ failure score(SOFA)scores for the prognosis of sepsis patients.Methods A total of 162 patients with sepsis admitted to the First People's Hospital of Nanyang City from January 2020 to December 2021 were collected and followed up for 3 months.They were divided into a death group(79 cases)and a survival group(83 cases)based on the outcome.Logistic multiple regression analysis was used to identify the risk factors for sepsis patient mortality,and ROC curve analysis was used to evalu-ate the predictive value of PCT combined with SOFA score for the prognosis of sepsis patients.Results Compared with the survival group,the proportion of patients aged ≥ 60 years in the death group in-creased.Body temperature,heart rate,acute physiological and chronic health(APACHE Ⅱ)score,C-reactive protein(CRP)level,SOFA score,serum interleukin-6(IL-6),interleukin-8(IL-8),interleu-kin-10(IL-10),tumor necrosis factor-α(TNF-α),and PCT were all elevated in the death group(P＜0.05).Further logistic multiple regression analysis showed that elevated PCT and SOFA scores were risk factors for mortality in sepsis patients(P＜0.05).PCT and SOFA scores had certain predictive value for the prognosis of sepsis patients,and the combined predictive value of PCT+SOFA score was better than that of each indicator alone(P＜0.05).Conclusion Elevated PCT and SOFA scores are risk factors for mortality in sepsis patients,and the combined evaluation of the two has higher predic-tive value for the prognosis of sepsis patients.
关键词
脓毒症/血清降钙素原/序贯器官衰竭评分/预后/预测
Key words
Sepsis/Serum procalcitonin/Sequential organ failure assessment/Prognosis/Predic-tion
维普
万方数据