Analysis of the efficacy of intermittent pneumatic compression device combined with low-molecular-weight heparin in preventing deep vein thrombosis after laparoscopic hysterectomy
Objective To investigate the effect of low-molecular-weight heparin(LMWH)com-bined with intermittent pneumatic compression device(IPC)in preventing the formation of deep vein thrombosis(DVT)in the lower extremities of patients undergoing laparoscopic hysterectomy.Methods A total of 122 patients with high risk of DVT after laparoscopic hysterectomy in Yongmei Group General Hospital from May 2022 to December 2023 were selected and randomly divided into a control group and an observation group,with 61 patients in each group.The control group was treated with LMWH after surgery,while the observation group was treated with LMWH combined with IPC to compress both lower extremities.The clinical efficacy,changes in coagulation function,postoperative recovery,and changes in thrombus elastography indexes were compared between the two groups.Re-sults After treatment,the incidence of thrombosis in the observation group was significantly lower than that in the control group(P＜0.05).The serum levels of PT and APTT were significantly high-er in the observation group than in the control group,while the levels of Fib and D-D were significant-ly lower(P＜0.05).The time of ambulation,disappearance of abdominal pain,and length of hospital stay were significantly shorter in the observation group than in the control group(P＜0.05).There were no significant differences in the thrombus elastography indexes K and Angle between the two groups(P＞0.05),but the R was significantly higher and the MA and CI were significantly lower in the observation group than in the control group(P＜0.05).Conclusion The combination of LMWH and IPC in patients after laparoscopic hysterectomy can prevent the formation of DVT,improve the thrombus elastography index levels,and can be promoted clinically.
Laparoscopic hysterectomyLow-molecular-weight heparinDeep vein thrombosis of the lower extremities
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