华北理工大学学报(医学版)2024,Vol.26Issue(5) :355-360.DOI:10.19539/j.cnki.2095-2694.2024.05.004

酒脂复合型急性胰腺炎的临床特点分析

Analysis of clinical characteristics of alcohol-hyperlipidemia associated acute pancreatitis

佟建华 车根 曹曦
华北理工大学学报(医学版)2024,Vol.26Issue(5) :355-360.DOI:10.19539/j.cnki.2095-2694.2024.05.004

酒脂复合型急性胰腺炎的临床特点分析

Analysis of clinical characteristics of alcohol-hyperlipidemia associated acute pancreatitis

佟建华 1车根 1曹曦2
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作者信息

  • 1. 内蒙古科技大学包头医学院 内蒙古包头 014040
  • 2. 鄂尔多斯市中心医院
  • 折叠

摘要

目的 探讨酒脂复合型急性胰腺炎(AHAP)的临床特点.方法 采用回顾性研究方法,收集鄂尔多斯市中心医院2022年1月2024年5月收治的急性胰腺炎患者161例,根据病因分为酒精性急性胰腺炎(AAP)、高脂血症急性胰腺炎(HLAP)和AHAP组.针对其基线资料,实验室检查指标、严重程度等进行分析与比较.结果 与HLAP组比较,AHAP组男性比例更高(P<0.05);AHAP组合并脂肪肝的比率高于AAP和HLAP组(P<0.05).AHAP组入院时甘油三酯(TG)、总胆固醇(TC)水平明显高于AAP组和HLAP组(P<0.05),且在住院早期阶段AHAP组重症患者比率更高.通过Logistic回归分析进一步证实,男性、合并脂肪肝和早期阶段重症胰腺炎(SAP)诊断率是AHAP的影响因素.结论 AHAP具有区别于单病因AAP和HLAP的临床特征,其中年男性发病高、合并脂肪肝比率更高,更易发展成为重症.

Abstract

Objective To investigate the clinical characteristics of alcohol-hyperlipidemia associat-ed acute pancreatitis(AHAP).Methods A retrospective study was conducted to collect 161 patients with acute pancreatitis admitted to our hospital from January 2022 to May 2024.Patients were divided into alcoholic acute pancreatitis(AAP),hyperlipidemia-induced acute pancreatitis(HLAP),and AHAP groups based on etiology.Baseline data,laboratory test indicators,and severity were analyzed and compared among the groups.Results Compared with the HLAP group,the AHAP group had a higher male proportion(P<0.05),and a higher rate of concurrent fatty liver than the AAP and HLAP groups(P<0.05).The levels of triglycerides(TG)and total cholesterol(TC)at admission in the AHAP group were significantly higher than those in the AAP and HLAP groups(P<0.05).Ad-ditionally,the proportion of severe patients was higher in the early stage of hospitalization in the AHAP group.Further Logistic regression analysis confirmed that male gender,concurrent fatty liver,and early-stage severe acute pancreatitis(SAP)diagnosis rate were influencing factors of AHAP.Con-clusion AHAP exhibits distinct clinical features from single-etiology AAP and HLAP,characterized by a higher incidence in middle-aged males,a higher rate of concurrent fatty liver,and a greater tend-ency to develop into severe pancreatitis.

关键词

酒精性胰腺炎/高脂血症性胰腺炎/酒脂复合型胰腺炎/临床特点

Key words

Alcoholic pancreatitis/Hyperlipidemia-induced pancreatitis/Alcohol-hyperlipi-demia associated acute pancreatitis/Clinical characteristics

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基金项目

内蒙古自治区卫生健康科技计划项目课题(202201594)

出版年

2024
华北理工大学学报(医学版)
河北联合大学

华北理工大学学报(医学版)

影响因子:0.569
ISSN:2095-2694
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