Study on Antioxidant and Anti-exercise Fatigue Effects of Tegillarca Granosa Extract
In order to develop and utilize the resources of Tegillarca granosa,and explore the antioxidant and anti-exercise fatigue effects of water extract and alcohol extract of Tegillarca granosa.1,1-diphenyl-2-picrylhydrazyl(DPPH),superoxide anion(O-2)and the ability to inhibit the fading of β-carotene were used to evaluate the in vitro antioxidant effect of the extract of Tegillarca granosa.The anti-exercise fatigue effect of Tegillarca granosa extract was investigated by measuring the stay time of rotating stick,swimming time after exhaustive load and the changes of related serum biochemical indexes in mice after exercise.The results showed that the ethanol extract of Tegillarca granosa had a strong ability to scavenge DPPH and O-2 free radicals and inhibit the fading of β-carotene linoleic acid system,and its half maximal inhibitory concentration(IC50)was 1.38,1.87 and 2.07mg/mL,respectively.In the high-dose group,the retention time of rotating rod was 64.10±1.86s,and the exhaustive swimming time was 102.55±2.49min,which showed a dose-effect relationship.The high-dose group of the water extract of Tegillarca granosa could increase the contents of liver glycogen and muscle glycogen in mice after exercise,and decrease the levels of urea nitrogen and blood lactic acid.The results were 16.36±0.42mg/g,2.56±0.22mg/g,7.84±0.31 mmol/L and 3.44±0.25mmol/L respectively.There was significant difference(P<0.05)between each group of the ethanol extract from Tegillarca granosa.This study provided reference for the deep development and utilization of Tegillarca granosa.
万方数据
维普
