Systematic Evaluation and Meta-analysis of Effects of Exercise Training on Vascular En-dothelial Function in High Fat/High Sugar Diets
Objective To systematically evaluate the improvement effect of high-intensity interval training(HIIT)compared to moder-ate intensity continuous training(MICT)on endothelial dysfunction at various time points after a high-fat/high sugar diet.Methods Retrieve relevant literature on the effects of exercise intervention on high-fat/high sugar dietary vascular endothelial function(FMD)in Pubmed,Web of Science,CNKI,and Wanfang databases.The search period was from database establishment to May 2024.After in-dependent screening of literature,extraction of data,and evaluation of literature quality by two researchers,data analysis was con-ducted using Review Manager 5.4 and STATA 17 software.Results A total of 8 articles were included,with a sample size of 107 peo-ple.The analysis results showed that compared with the control group,the vasodilation ability of the exercise group was significantly higher than that of the control group(WMD=-0.31,95％CI:-0.50～-0.12).Among the four time periods,exercise intervention showed the most significant difference in regulating FMD at 3 hours after meals(WMD=-0.31,95％CI:-0.50～-0.12),while the improvement effect on high sugar postprandial FMD was not significant(WMD=-0.32,95％CI:-0.54～-0.10).Conclusion Exercise can effectively regulate high-fat/high sugar postprandial FMD,and the regulatory effect of MICT is better than HIIT.However,the improvement effect of exercise on vascular endothelial dysfunction caused by high sugar diet is not significant.
sports traininghigh fat diethigh sugar dietvascular endothelial function
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