In this paper,network slicing security isolation technology based on 5G edge compu-ting is studied.Through the combination of virtualization technology(NFV and SDN),net-work physical resources can be flexibly divided and isolated.An analysis of application cases shows that the deployment of network slicing technology has improved resource utilization by 10%to 15%,reduced average communication latency by 33%,increased data access speed by 40%,reduced data breach rate from 2.5%to 0%,and reduced unauthorized access incidents by 66%.The results show that this technology can improve network performance,optimize re-source scheduling and ensure data security.