Clinical characteristics and early warning indicators of influenza A and influenza B in children
Objective To analyze the clinical characteristics and peripheral blood characteristics of influenza A and B(hereinafter referred to as influenza)in children,especially the significance of neutrop hil-to-lymphocyte ratio(NLR),in order to improve the understanding level of influenza in children and provide reference for early diagnosis of influenza in children.Methods A total of 428 children with fever and/or upper respiratory tract infection were selected.According to the results of influenza virus antigen,they were divided into influenza A virus(IAV)positive group(IAV group,n=172),influenza B virus(IBV)positive group(IBV group,n=132)and control group(n=124).The epidemiological characteristics,clinical manifestations and routine examination results of peripheral blood were reviewed and analyzed.Results There were no significant differences in while blood cell(WBC)levels among the three groups(P＞0.05).The levels of neutrophils,lymphocytes,NLR and C-reactive protein(CRP)in peripheral blood of IAV group and IBV group were significantly different from those of control group,respectively(P＜0.05).However,there was no significant difference in neutrophils,lymphocytes,NLR,and CRP between IAV group and IBV group(P＞0.05).Conclusion The proportion of neutrophils,lymphocytes,CRP and NLR in peripheral blood routine can provide reference for early diagnosis of influenza in children.
万方数据
维普
