Perinatal Risk Factors for Late Preterm Neonatal Respiratory Distress Syndrome with Acute Respiratory Distress Syndrome
Objective:To investigate the perinatal risk factors for late preterm neonatal respiratory dis-tress syndrome(NRDS)with acute respiratory distress syndrome(ARDS).Methods:A retrospective analy-sis was conducted on cases of late preterm NRDS admitted to the neonatal intensive care unit of a certain hos-pital from September 2019 to January 2023.The patients were divided into the observation group(NRDS with ARDS)and the control group(simple NRDS)according to whether or not they developed ARDS.The perina-tal risk factors of the two groups were compared.Results:A total of 92 cases were included,with 44 cases in the observation group and 48 cases in the control group.There were no significant differences in sex,gesta-tional age,body weight,and mode of delivery between the two groups(P>0.05).The incidence of late-term respiratory tract infection,late-term vaginitis,late-term vitamin D deficiency,meconium-stained amniotic fluid,and asphyxia was higher in the observation group than in the control group,with statistically significant differences(P<0.05).The incidence rates of gestational diabetes,gestational hypertension,prenatal lung stimulation therapy,premature rupture of membranes,umbilical cord entanglement,placenta previa,placen-tal abruption,low body weight,and intrauterine distress revealed no statistical significance in both groups(P>0.05).The variables with statistical significance in the univariate analysis(late-term respiratory tract infec-tion,late-term vaginitis,late-term vitamin D deficiency,meconium-stained amniotic fluid,and asphyxia)were included in the logistic regression analysis.The results of the stepwise logistic regression analysis showed that late-term respiratory tract infection(OR=9.613,95%CI 1.056-87.489,P<0.05),late-term vaginitis(OR=11.469,95%CI 1.286-102.294,P<0.05),and late-term vitamin D deficiency(OR=7.499,95%CI 1.887-29.802,P<0.05)were all statistically significant,and were associated with late preterm NRDS with ARDS.Conclusion:Late-term respiratory tract infection,late-term vaginitis,and late-term vitamin D deficiency are independent risk factors for late preterm NRDS with ARDS.
万方数据
维普
