Tremor Analysis and External Anal Sphincter Electromyography in Patients with Parkinson's Disease and P-Type Multiple System Atrophy
Objective:To investigate the differences in tremor analysis and external anal sphincter elec-tromyography(EAS-EMG)in Parkinson's disease(PD)and P-type Multiple system Atrophy patients(MSA-P).Methods:Fifty PD patients and twenty-five MSA-P patients treated at the Department of Neurology,Affiliated Hospital of Xuzhou Medical University,were selected.According to the H&Y staging,PD patients were divided into early-middle stage PD group(H&Y 0-3,27 cases)and late-stage PD group(H&Y 4～5,23 cases),along with the MSA-P group(25 cases).Tremor analysis and EAS-EMG were performed for all three groups,and the differences in various indices of tremor analysis and EAS-EMG among the three groups were analyzed.Results:The incidence of resting tremor was higher in the PD group compared to the MSA-P group(P<0.05),with no significant differences in tremor frequency and postural tremor incidence.In the early-middle stage PD group,both resting tremor and postural tremor frequencies were higher than in the late-stage PD group(P<0.05),with resting tremor being predominant in both groups.However,there were no statistically significant differences in the incidence of resting tremor and postural tremor between the two groups(P>0.05).The incidence of resting tremor was higher in the early-middle stage PD group compared to the MSA-P group(P<0.05),with no significant difference in the incidence of postural tremor.Compared with the PD group,the MSA-P group had a prolonged average duration of motion unit of the anal sphincter during slight contraction(MUAP),a significantly higher percentage of polyphasic waves,and a higher incidence of satellite potentials(P<0.05).In the late-stage PD group compared to the early-middle-stage PD group,there was a prolonged average duration of MUAP,a significantly higher percentage of polyphasic waves,and a higher incidence of satellite potentials(P<0.05).Compared to the MSA-P group,the early-middle stage PD group had a shorter average duration of MUAP(P<0.05),a lower percentage of polyphasic waves,and a lower incidence of satellite potentials(P<0.05).Conclusion:Tremor analysis and EAS-EMG are associated with the progression of Parkinson's disease and may provide a basis for differentiating between MSA-P and early-middle-stage PD patients.
Parkinson's diseaseMultiple system atrophyTremor analysisExternal anal sphincter electromyography
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