首页|CT肺动脉成像与急性肺栓塞严重程度及短期预后的相关性研究

CT肺动脉成像与急性肺栓塞严重程度及短期预后的相关性研究

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目的:评估肺动脉及心功能 CT 参数与急性肺栓塞患者 30d 不良预后的关系,为急性肺栓塞患者的快速风险分层提供信息。方法:本研究回顾性分析了2018 年5 月至2020 年5 月我院行CT-PA检查确诊为急性肺动脉栓塞且随访 30d 者共 243 例。在横轴位图像上,测量主肺动脉(MPA)及主动脉(AO)比值、左(LPA)、右(RPA)肺动脉最大径线及右、左心室之间的最大短径比(即 RVD/LVD),在工作站测量肺动脉干高度和体积。根据30d预后、肺栓塞的严重程度及分型进行分组,对各参数进行比较。结果:手术或制动史、心率、肺栓塞分型和治疗方式在两组间差异有统计学意义(P<0。05);预后不良组LPA、RVD/LVD值均大于预后良好组(P<0。05);在根据栓塞部位和严重程度进行分组中发现,MPA/AO、MPA、RPA、LPA、PAV、PAOI、RVD/LVD、室间隔移位及腔静脉反流于两组间均有统计学差异(P<0。05);右室与左室径线比值(RVD/LVD)预测中重度肺栓塞的AUC值最大,特异度最高。结论:右室与左室径线(RVD/LVD)比值可作为急性肺栓塞预后日常评估的首选指标。肺动脉干体积(PAV)可以作为判断急性肺栓塞严重程度的新指标。此外,MPA、RPA、LPA 和腔静脉反流及室间隔移位对肺栓塞严重程度有一定预测价值,能够为临床的个性化治疗方案提供较可靠依据。
Study on the Correlation between CT Pulmonary Artery Imaging and the Severity and Short-term Prognosis of Acute Pulmonary Embolism
Objective:To evaluate the relationship between CT parameters of pulmonary artery and car-diac function and 30-day adverse prognosis in patients with acute pulmonary embolism,and to provide infor-mation for rapid risk stratification in patients with acute pulmonary embolism.Methods:A total of 243 pa-tients who were diagnosed with acute pulmonary embolism by CTPA examination in our hospital and followed up for 30 days were retrospectively analyzed in this study.The ratio of the main pulmonary artery(MPA)to the aorta(AO),the maximum diameter of the left(LPA)and right(RPA)pulmonary artery,and the maxi-mum short diameter ratio between the right and left ventricles(RVD/LVD)were measured on the transverse axis image,and the height and volume of the pulmonary trunk were measured at the workstation.The patients were grouped according to 30-day prognosis,the severity of pulmonary embolism,and embolism type,and va-rious parameters were compared.Results:There were statistically significant differences between the two groups in terms of surgery or immobilization history,heart rate,pulmonary embolism type,and treatment methods(P<0.05);The LPA and RVD/LVD values in the poor prognosis group were greater than those in the good prognosis group(P<0.05);In the grouping based on the location and severity of the embolism,there were statistically significant differences between the two groups in terms of MPA/AO,MPA,RPA,LPA,PAV,PAOI,RVD/LVD,interventricular septal shift,and vena cava reflux(P<0.05);The ratio of right ventricular to left ventricular diameters(RVD/LVD)had the highest AUC value and specificity for pre-dicting moderate to severe pulmonary embolism.Conclusion:The ratio of right ventricular to left ventricular diameters(RVD/LVD)can be used as the primary indicator for daily assessment of the prognosis of acute pul-monary embolism.The volume of the pulmonary artery trunk(PAV)can serve as a new indicator for determi-ning the severity of acute pulmonary embolism.Additionally,MPA,RPA,LPA,vena cava reflux,and inter-ventricular septal shift have certain predictive values for the severity of pulmonary embolism,providing a more reliable basis for clinical personalized treatment plans.

Pulmonary artery CTAPulmonary embolismAdverse prognosis

胡杰、郑同同、刘晓伟、甄玉莎

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河北省石家庄市第三医院影像中心,河北 石家庄 050000

河北医科大学第二医院放射科,河北 石家庄 050000

肺动脉CTA 肺栓塞 不良预后

河北省卫生健康委员会指导性课题

20242021

2024

河北医学
河北省医学会

河北医学

CSTPCD
影响因子:1.915
ISSN:1006-6233
年,卷(期):2024.30(6)
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