首页|培元健脾针药方治疗2型糖尿病合并肥胖症临床疗效观察

培元健脾针药方治疗2型糖尿病合并肥胖症临床疗效观察

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目的:旨在通过观察针药结合"固本培元,健脾和胃"法治疗肥胖型 2 型糖尿病患者的临床疗效。方法:选用2019 年3 月至2022 年3 月80 例肥胖型 2 型糖尿病患者,依照随机数字表法分为两组,每组40 例。对照组予盐酸二甲双胍片结合米格列醇片。医治组在对照组基础上,加用针药联合疗法。两组均医治30d(1 个疗程)。比较两组治疗前后相关观察指标的差异。结果:医治组总有效率高于对照组(P<0。05)。两组治疗后体重指数(Body Mass Index,BMI)、总胆固醇(Total cholesterol,TC)、甘油三脂(Triglyceride,TG)、低密度脂蛋白(Low-density lipoprotein cholesterol,LDL-C)、空腹血糖(Fast-ing plasma glucose,FPG)、血清空腹胰岛素(Fasting insulin serum,FINS)、胰岛素指数(HOMA-Insulin Resistance,HOMA-IR)与医治组比较有显著性差异(P<0。05),且治疗组均优于对照组(P<0。05)。在降低腰臀比(Waist-to-hip ratio,WHR)、胰岛素敏感性指数(Insulin action index,IAI)方面差异无统计学意义(P>0。05),阐明医治组和对照组在降低 WHR、IAI 方面无显著差异。结论:针药结合"固本培元,健脾和胃"法治疗肥胖型2 型糖尿病临床疗效确切,轻身、减脂、恢复血糖水平,治疗胰岛素抵抗状态成效卓著,尤其对提高FINS、高密度脂蛋白(High-density lipoprotein cholesterol,HDL-C)、降低TC、LDL-C方面成效突出。对降低BMI、FPG、TG、HOMA-IR作用值得肯定,无副作用,值得临床推行运用。
Clinical Observation on Therapeutic Efficacy of Peiyuanjianpi Acupuncture and Medicine Prescription on Type 2 Diabetes Mellitus Complicated with Obesity
Objective:To observe the clinical effect of acupuncture and medicine combined with"Gubenpeiyuan,jianpihewei"in the treatment of obese type 2 diabetes.Methods:80 obese patients with type 2 diabetes mellitus from March 2019 to March 2022 were selected and divided into 2 groups with 40 patients in each group according to the random number table method.The control group was given metformin hydrochlo-ride tablets combined with miglitol tablets.Based on the control group,the treatment group was added with needle and drug combination therapy.Both groups were treated for 30 days(1 course).The differences of rel-evant observation indexes before and after treatment were compared between the two groups.Results:The to-tal effective rate of the treatment group was higher than that of the control group(P<0.05).There were sig-nificant differences in BMI,FPG,FINS,HOMA-IR,TC,TG,and LDL-C between the two groups after treatment compared with before treatment(P<0.05),and the treatment group was superior to the control group(P<0.05).There was no obvious statistical difference in reducing WHR and IAI(P>0.05),indica-ting that there was no remarkable difference in the reduction of WHR and IAI between the treatment group and the control group.Conclusion:Acupuncture and medicine combined with"Gubenpeiyuan,jianpihewei"has definite clinical efficacy in the treatment of obesity-type 2 diabetes mellitus.It is effective in reducing body weight,reducing fat,restoring blood glucose level,and treating insulin resistance,especially in improving FINS,HDL-C,and reducing TC and LDL-C.The effect of reducing BMI,FPG,TG and HOMA-IR is wor-thy of affirmation,without side effects,and worthy of clinical application.

Obese type 2 diabetesAcupuncture therapyChinese medicine therapy

祝海锐、刘佳

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河北省承德市中医院,河北 承德 067000

肥胖型2型糖尿病 针刺疗法 中药疗法

2021年承德市科学技术研究与发展计划项目

202102A003

2024

河北医学
河北省医学会

河北医学

CSTPCD
影响因子:1.915
ISSN:1006-6233
年,卷(期):2024.30(6)
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