摘要
目的:探究血清BNP、TFC、CO、Scr等容量负荷评估指标与收缩功能障碍性心力衰竭患者短期预后的关系.方法:连续选取2021年11月至2023年1月于承德市中心医院心血管内科住院的收缩功能障碍性(LVEF＜50％)心力衰竭患者93例,记录患者出院后90d内出现心衰症状和体征加重、心血管性再就诊和(或)再住院以及心因性死亡等情况.根据预后情况分为两组:预后良好组和预后不良组.结果:共完成随访93例患者,预后不良31人.预后不良组患者的LVEF、CO、冠心病患病率均低于预后良好组(P＜0.05);预后不良组患者的BNP、cTnⅠ、TFC、Scr均高于预后良好组(P＜0.05).其中容量负荷评估指标BNP、TFC、CO、Scr是收缩功能障碍性心力衰竭患者出院后90天内发生不良预后的影响因素(P＜0.05).结论:容量负荷评估指标BNP、TFC、CO、Scr是收缩功能障碍性心力衰竭患者短期预后的影响因素,对其短期预后或可具有预测作用,对收缩功能障碍性心力衰竭患者临床治疗具有指导意义.
Abstract
Objective:To explore the relationship between serum BNP,TFC,CO,Scr and the short-term prognosis of patients with systolic dysfunction heart failure.Methods:A total of 93 patients with systolic dysfunction(LVEF＜50％)heart failure admitted to the cardiovascular Department of Chengde Central Hospi-tal from November 2021 to January 2023 were selected.Exacerbation of signs and symptoms of heart failure,cardiovascular re-visits and/or re-hospitalization,and cardiac death were recorded within 90 days after dis-charge.They were divided into two groups according to the prognosis:good prognosis group and bad prognosis group.Results:A total of 93 patients were followed up,31 of whom had poor prognosis.LVEF,CO and the prevalence of coronary atherosclerotic heart disease in the poor prognosis group was lower than that in the good prognosis group,and the difference was statistically significant(P＜0.05).BNP,cTnⅠ,TFC and Scr in the poor prognosis group were higher than those in the good prognosis group,and the difference was statistically significant(P＜0.05).Among them,BNP,TFC,CO and Scr are the factors influencing the adverse prognosis of patients with systolic dysfunction heart failure within 90 days after discharge(P＜0.05).Conclusion:Vol-ume load evaluation indexes BNP,TFC,CO and Scr are influential factors for the short-term prognosis of pa-tients with systolic dysfunction heart failure,and may have a predictive effect on their prognosis,and have guiding significance for clinical treatment of patients with heart failure.
基金项目
2020年承德市科学技术研究与发展计划项目(202006A024)
维普
万方数据