Comparative Study of Remifentanil Combined with Propofol versus Propofol Alone in Anesthesia for Hysteroscopic Electrosurgical Procedures
Objective:To investigate the application efficacy of two total intravenous anesthesia regi-mens,remifentanil combined with alfentanil versus propofol combined with alfentanil,during hysteroscopic electrosurgical procedures.Methods:From January 2023 to June 2023,a total of 107 patients undergoing hys-teroscopic electrosurgical procedures were included and randomly allocated using a random number table into a control group(n=53)receiving propofol combined with alfentanil anesthesia and an observation group(n=54)receiving remifentanil combined with alfentanil anesthesia.Pain intensity(evaluated using VAS scores),sedation levels(assessed by Ramsay Sedation Scale),vital signs,Modified Aldrete Score(MAS),and ad-verse reactions were compared between the two groups.Results:Compared with the control group,the obser-vation group showed significantly lower VAS scores at 2 hours and 12 hours postoperatively(P＜0.05)and higher Ramsay Sedation Scale scores at 2 hours postoperatively(P＜0.05).There were no significant differ-ences in preoperative heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),and oxygen saturation(SPO2)between the two groups(P＞0.05).However,HR,SBP,DBP,and SPO2 levels were significantly higher in the observation group than in the control group at 5 minutes after the start of surger-y and at 2 hours postoperatively(P＜0.05).Significant group effects,time effects,and interaction effects were observed for VAS scores,Ramsay Sedation Scale scores,and vital signs(P＜0.05).The observation group had higher Modified Observer's Assessment of Alertness/Sedation(MOAA/S)scores at 1,3,and 5 mi-nutes after surgery compared to the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Remifentanil combined with alfentanil provides better pain control and sedation during early postoperative period in patients undergo-ing hysteroscopic electrosurgical procedures compared to propofol combined with alfentanil.Patients recover faster to a clear consciousness state,and their vital signs are more stable during anesthesia.
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