Efficacy and Safety Analysis of Different Power HoLEP Combined with Holmium Laser Lithotripsy in the Treatment of Benign Prostatic Hyperplasia with Bladder Stones
Efficacy and Safety Analysis of Different Power HoLEP Combined with Holmium Laser Lithotripsy in the Treatment of Benign Prostatic Hyperplasia with Bladder Stones
Objective:To study the efficacy and safety of different powers of holmium laser enucleation of the prostate(HoLEP)combined with holmium laser cystolithotripsy(HLC)in the treatment of benign pros-tatic hyperplasia(BPH)with bladder stones.Methods:The clinical data of 110 patients with BPH combined with bladder stones admitted to Danyang People's Hospital from January 2019 to January 2024 were collected.According to the surgical methods,patients who received high-power HoLEP combined with HLC were includ-ed in the HP group(n=62),and patients who adopted low-power HoLEP combined with HLC were enrolled as the LP group(n=48).Perioperative indicators,urinary function,stress indicators,and postoperative complications were compared between both groups.Results:The surgical time,excised tissue mass,bladder irrigation time and postoperative urinary catheter retention time with(68.49±15.36)min,(41.42±10.59)g(1.86±0.66)d and(2.34±0.85)d in the HP group were not statistically different form(70.15±15.71)min,(42.81±9.93)g,(1.81±0.72)d and(2.58±0.92)d in the LP group(P>0.05).The time of glan-dular enucleation and hospital stay with(35.80±7.21)min and(3.62±0.64)d in the HP group were shor-ter than(41.64±7.83)min and(3.86±0.50)d in the LP group,and the enucleation efficiency and de-crease rate of hemoglobin with(1.15±0.25)g/min and(8.05±1.58)g/L were higher than(1.02±0.18)g/min and(7.36±1.72)g/L in the LP group(P<0.05).At 3 months after surgery,the differences of Qmax,PVR and PSA before and after treatment were not statistically significant between the HP group and the LP group(P>0.05).The differences of SP,PGE2 and NE before and after treatment revealed no statistical differences between the HP group and the LP group at 24 hours after surgery(P>0.05).There was no statis-tical significance in incidence of postoperative complications between the HP group(12.88%)and the LP group(10.40%)(P>0.05).Conclusion:High-power and low-power HoLEP combined with HLC have similar efficacy in the treatment of BPH with bladder stones.High-power HoLEP has higher enucleation effi-ciency,and shorter glandular enucleation time and hospital stay,and low-power HoLEP has better hemostatic effect.
关键词
低功率钬激光前列腺剜除术/高功率钬激光前列腺剜除术/钬激光碎石术/良性前列腺增生/膀胱结石
Key words
Low-power holmium laser enucleation of the prostate/High-power holmium laser enu-cleation of the prostate/Holmium laser cystolithotripsy/Benign prostatic hyperplasia/Bladder stones
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万方数据