Developments on exploring the immune correlation between ischaemic stroke and intestinal flora based on brain-gut axis
It has been shown that the human gut is settled with a large microbiota,which is involved in the regu-lation of the body's immune homeostasis and is closely related to the development of ischaemic stroke.The dis-covery of the microbial-gut-brain axis links the gut to the brain and plays an important role in human health and disease processes.This paper reviews the regulatory mechanisms of the microbial-gut-brain axis,the modulation of gut flora and its metabolites after stroke,and the possible mechanisms of the brain-gut axis based on brain and gut immune responses after ischaemic stroke.These studies provide important implications for exploring new di-rections of gut and brain immunotherapy after stroke and improving stroke prognosis.
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