首页|基于MRI影像组学在乳腺癌分子分型的研究进展

基于MRI影像组学在乳腺癌分子分型的研究进展

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乳腺癌严重影响女性身心健康,是女性最常见的恶性肿瘤,其依据病理不同进行分子分型,早期识别病理分型和靶向治疗是改善患者预后的关键。病理虽为金标准也存在一定不足,如操作的有创性、标本取材的局限性以及检测时间要求的限制性。影像组学通过深度挖掘影像图像多维度特征,将肿瘤的异质性进行量化处理,采用一种无创性、简便的方法对肿瘤的生物学特性进行综合评价,在乳腺癌分子分型的发现、预测淋巴结转移、制订治疗方案、评估治疗效果、判断患者预后等方面已得到广泛应用。现拟基于MRI影像组学特征对乳腺癌分子分型的应用现状进行综述。
Advances on MRI radiomics in molecular typing of breast cancer
Breast cancer is the most common malignant tumor in women,which seriously affects the physical and mental health of women.Molecular classification according to pathology,early identification of pathological clas-sification and targeted therapy play a decisive role in ameliorating prognosis of patients.Although pathology is the gold standard,there are some shortcomings,such as the invasiveness of operation,the limitation of sampling and the limitation of testing time.By deeply mining the multi-dimensional features of the image,radiomics quan-tifies the heterogeneity of the tumor,and uses a non-invasive and simple method to comprehensively evaluate the biological characteristics of the tumor,it has been widely used in the discovery of molecular classification of breast cancer,prediction of LNM,formulation of treatment plan,evaluation of treatment effect,prognosis of pa-tients and so on.In this paper,the application of molecular typing of breast cancer based on MRI radiomics characteristics is reviewed.

breast cancermolecular typingradiomicsmagnetic resonance imaging

李昊、侯岩、殷小平

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河北大学附属医院放射科,河北 保定 071000

河北省保定市第一中心医院超声一科,河北 保定 071000

河北省炎症相关肿瘤精确影像学重点实验室,河北 保定 071000

乳腺癌 分子分型 影像组学 磁共振成像

河北省高层次人才项目

B20231008

2024

医学研究与教育
河北大学

医学研究与教育

影响因子:0.675
ISSN:1674-490X
年,卷(期):2024.41(2)
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