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精神分裂症复发现状及影响因素分析

Analysis of the current status and influencing factors of schizophrenia relapse

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目的 探讨精神分裂症复发情况,分析其影响因素.方法 以保定市某精神专科医院确诊的精神分裂症患者为研究对象.利用服药依从性量表、自知力与治疗态度量表、贬低-歧视感知量表、社会支持量表等调查工具,采用面对面方法收集患者资料,分析精神分裂症复发的影响因素.结果 共收集 430 例患者资料,其中 199 例患者复发,复发率为 46.27%.二分类 Logistic 回归分析显示,病程(OR=10.294,P<0.001)、病耻感(OR=9.087,P<0.001)、是否经历过应激创伤事件(OR=2.162,P=0.017)、精神分裂症家族史(OR=3.066,P=0.001)是精神分裂症复发的危险因素;家庭人均月收入(OR=0.300,P=0.020;OR=0.075,P<0.001;OR=0.096,P=0.001)、自知力与治疗态度(OR=0.570,P=0.539;OR=0.097,P=0.011;OR=0.018,P=0.001)、服药依从性(OR=0.189,P<0.001)是精神分裂症复发的保护因素.结论 精神分裂症的复发率较高,病程较长、自知力与治疗态度较差、病耻感较重、有应激创伤事件、有精神分裂症家族史、家庭人均月收入较低、服药依从性差是精神分裂症复发的主要因素.
Objective To explore the recurrence of schizophrenia and analyze its influencing factors.Methods The study was conducted among patients diagnosed with schizophrenia at a specialized psychiatric hospital in Baoding city.Data were collected face-to-face using various scales,including the medication adherence scale,insight and treatment attitude scale,perceived devaluation-discrimination scale,and social support scale to ana-lyze factors influencing schizophrenia recurrence.Results A total of 430 patients were included,among whom 199 experienced a recurrence,yielding a recurrence rate of 46.27%.Binary logistic regression analysis revealed that longer illness duration(OR=10.294,P<0.001),stigma(OR=9.087,P<0.001),history of traumatic stress(OR=0.389,P=0.017),and a family history of schizophrenia(OR=3.066,P=0.001)were risk factors for recurrence.Additionally,higher monthly per capita family income(OR=0.300,P=0.020;OR=0.075,P<0.001;OR=0.096,P=0.001),better insight and treatment attitude(OR=0.570,P=0.539;OR=0.097,P=0.011;OR=0.018,P=0.001),and higher medication adherence(OR=0.189,P<0.001)were identified as protective factors.Conclusion In conclusion,the recurrence rate of schizophrenia remains high.Patients with longer illness durations,higher levels of stigma,traumatic stress history,family history of schizo-phrenia,lower monthly per capita family income,poorer insight and treatment attitudes,and lower medication adherence are at greater risk of recurrence.

schizophreniarecurrenceinfluencing factors

赵紫琪、王丽娜、安瑞琦、张红杰

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河北大学公共卫生学院,河北 保定 071000

河北省第六人民医院护理部,河北 保定 071000

精神分裂症 复发 影响因素

2024

医学研究与教育
河北大学

医学研究与教育

影响因子:0.675
ISSN:1674-490X
年,卷(期):2024.41(6)