Clinical efficacy of modified Shentong Zhuyu Decoction combined with pramipexole on patients with restless legs syn-drome of phlegm blood stasis blocking
Clinical efficacy of modified Shentong Zhuyu Decoction combined with pramipexole on patients with restless legs syn-drome of phlegm blood stasis blocking
Objective To observe the clinical efficacy of modified Shentong Zhuyu Decoction combined with pramipexole(PMX)on patients with restless legs syndrome(RLS)of phlegm blood stasis blocking.Methods A total of 50 RLS patients(phlegm blood stasis blocking)were randomly assigned into the treatment group(n =25)and the control group(n =25).All patients were managed by PMX,and those in the treatment group were additionally treated with modified Shentong Zhuyu Decoc-tion.The treatment continued for 2 courses(1 course for 1 week),the aim was to compare International Restless Legs Syndrome Severity Scale(IRLS),Pittsburgh Sleep Quality Index(PSQI),traditional Chinese medicine(TCM)symptom score.The cura-tive effect was assessed.Results The overall effective rate in the treatment group was better than that in the control group(92.00%[23/25]vs 60.00%[15/25],[P＜0.05],respectively).After treatment,IRLS,PSQI,TCM symptom scores in the both groups were significantly decreased(P＜0.05),which decreased notably in the treatment group(P＜0.05).Conclu-sion For RLS patients(phlegm blood stasis blocking),modified Shentong Zhuyu Decoction combined with PMX has significant and definite clinical efficacy,which can effectively improve clinical and TCM symptoms,sleep quality,it is easy to operate,and with good safety.
关键词
不宁腿综合征/普拉克索/身痛逐瘀汤/痰瘀痹阻/中西医结合疗法
Key words
Restless legs syndrome/Pramipexole/Shen-tong Zhuyu Decoction/Phlegm blood stasis blocking/Integrated traditional Chinese and Western medicine therapy
维普
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