Correlation between the nature of pulmonary nodules and the constitution and syndrome of traditional Chinese medicine
Objective To observe the correlation between the nature of pulmonary nodules(PNs)and theconstitution and syndrome of traditional Chinese medicine(TCM).Methods From July 2019 to December 2020,a total of 271 patients with PNs treated in our hospital were recruited.The diameter,density,and number of PNs were recorded.Stratified by the diam-eter,PNs were divided into≤4 mm,4～6 mm,6～8 mm,and＞8 mm.Stratified by the imaging characteristic,PNs were di-vided into pulmonary solid nodules,pure ground-glass nodules,and mixed nodules.Stratified by the number of PNs,they are divided into solitary pulmonary nodules(SPNs)and multiple pulmonary nodules(MPNs).The TCM constitutions of patients with PNs were divided into 9 types,including thegentleness constitution,Qi-deficiency constitution,Yang-deficiency constitution,Yin-deficiency constitution,phlegm-dampness constitution,damp-heat constitution,blood stasis constitution,Qi-stagna-tion constitution,and special intrinsic quality constitution.The TCM syndromes were divided into 5 types,including the lung Qi deficiency syndrome,Qi and Yin deficiency syndrome,blood stasis syndrome,phlegm heat obstructing lung syndrome,and liver Qi stagnation syndrome.Baseline characteristics of patientswere collected,and the correlation of the diameter,density and num-ber of PNs with the constitution and syndrome of TCM was analyzed.Results Among the 271 patients with PNs,the incidence of PNs(164 cases,60.5%)was the highest in the elderly group(＞60 years old).PNs with a diameter of 4 to 6 mm(134 cases,49.5%)were the most majority.Most of PNs were pure ground-glass nodules(160 cases,59.0%)and MPNs(198 cases,73.1%).The TCM constitutions of patients with PNs were mainly Qi-deficiency constitution(64/271,23.6%),Qi-stagnation constitution(60/271,22.1%),and damp-heat constitution(41/271,15.1%).The TCM syndrome types were mainly lung Qi deficiency syndrome(93/271,34.3%),Qi and Yin defi-ciency syndrome(52/271,19.2%),and blood stasis syndrome(48/271,17.7%).The diameter of PNs was correlated with TCM constitution.PNs with the diameter≤4 mmwere mainly detected in patients with the Qi-stagnation constitution(P＜0.05),and those with a diameter of 4 to 6 mm were least detected in them(P＜0.05).PNs with diameter＞8 mm were more common in patients with blood stasis constitution(P＜0.05).The correlation between the density of PNs and TCM syndrome type was identified.Pure ground-glass nodules were mostly detected in patients with liver Qi stagnation syndrome(P＜0.05).There was a correlation between the number of PNs and TCM syndrome type.Most patients with liver Qi stagnation syndrome had MPNs(P＜0.05),and SPNs were occasionally detected(P＜0.05).Conclusion The diameter,density,and number of PNs are correlated with the constitution and syndrome of TCM.In clinical diagnosis and treatment,pulmonary nodules can be diagnosed and treated more accurately based on the correlation between the nature of the pulmonary nodules and the constitution and syn-drome of TCM.
Pulmonary nodulesTraditional Chinese medicine(TCM)constitutionTraditional Chinese medicine(TCM)syndrome typeCorrelation
万方数据
维普
