Clinical study on modified Wuling Powder combined with Zhuanggu Guanjie capsule on elderly intertrochanteric frac-ture
Objective To analyze the curative effect of modified Wuling Powder combined with Zhuanggu Guanjie cap-sule on elderly intertrochanteric fracture.Methods From December 2019 to December 2021,a total of 165 cases of elderly in-tertrochanteric fracture were randomly assigned into the control group(n =79)and the treatment group(n =86).All patients were managed by Zhuanggu Guanjie capsule,and patients in the observation group were additionally given modified Wuling Pow-der,the treatment was performed for 3 weeks for statistical efficacy.The key observation was the time to deswelling and fracture healing,the scores of visual analogue scale(VAS)score,Harris hip score(HHS),the inflammatory factor indexes(Interleukin 6[IL-6],IL-10,and tumor necrosis factor α[TNF-α]),andtraditional Chinese medicine(TCM)symptoms(complex-ion,tinnitus,soreness and weakness of waist and knees,weakness of limbs and lassitude)scores,as well as complication before and after treatment between the two groups.Results The total effective rate in the treatment group was better than that of the control group(96.51%[83/86]vs79.75%[63/79],P＜0.05),and the complications rates was significantly lower than that of the control group(4.65%(4/86)vs17.72%(14/79),P＜0.05).After treatment,the time to deswelling and fracture healing in the treatment group was significantly shorter than that in the control group(P＜0.05).Significantly decreased VAS scores(P＜0.05)and significantly increased HHS scores(P＜0.05)were detected in the both groups,and there were statistical differences in VAS and HHS between the treatment group and the control group(all P＜0.05).The levels of serum IL-6,IL-10 and TNF-α in the two groups were significantly decreased(P＜0.05),and the decrease in the treatment group was more obvious(P＜0.05).The TCM symptoms(complexion,tinnitus,soreness and weakness of waist and knees,limb weakness and mental fatigue)scores in the two groups were significantly decreased(P＜0.05),which were significantly lower in the treatment group than the control group(P＜0.05).Conclusion For elderly intertrochanteric fracture,modified Wuling Powder combined with Zhuanggu Guanjie capsule can effectively improve the clinical symptoms have a definite effect.It can sig-nificantly promote wound edema regression and fracture healing,relieve pain symptoms,improve hip joint function,improve TCM symptoms,and reduce complications.It may inhibit the inflammatory response by reducing the levels of IL-6,IL-10 and TNF-α.
FractureFemoral trochanterWuling PowderChinese medicine therapy
万方数据
维普
