首页|局部围针刺法联合超声电导透入治疗胸壁结核的临床观察

局部围针刺法联合超声电导透入治疗胸壁结核的临床观察

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目的 观察局部围针刺法联合超声电导透入治疗胸壁结核的临床疗效.方法 选取2015 年8 月至2021年8 月胸壁结核患者161 例,按照随机数字表法分为2 组,在均予抗结核药物治疗的基础上,对照组 78 例予异烟肼、利福平超声电导透入治疗,治疗组83 例在对照组基础上联合局部围针刺法治疗.2 组均治疗2 个月后统计疗效,比较2 组治疗前后炎症指标[包括血清C反应蛋白(CRP)、红细胞沉降率(ESR)及中性粒细胞计数(NEU)]及免疫指标(T淋巴细胞亚群CD3+、CD4+、CD8+及 CD4+/CD8+)水平变化情况.结果 治疗组愈显率 63.8%(53/83),对照组愈显率34.6%(27/78),治疗组愈显率高于对照组(P<0.05).与本组治疗前比较,治疗组治疗后炎症因子血清ESR、NEU及CRP水平均降低(P<0.05),对照组治疗后仅血清ESR及CRP水平降低(P<0.05),其中治疗组治疗后血清ESR、NEU及CRP水平均低于对照组(P<0.05).与本组治疗前比较,2 组治疗后免疫指标T淋巴细胞亚群CD3+、CD4+及CD8+水平均升高(P<0.05),且治疗组治疗后T淋巴细胞亚群CD3+、CD4+及CD8+水平均高于对照组(P<0.05),但2 组治疗前后CD4+/CD8+水平变化比较差异均无统计学意义(P>0.05).结论 局部围针刺法联合超声电导透入治疗胸壁结核疗效确切,可有效促进包块消退,抑制炎性反应,改善患者免疫功能,安全可靠.
Clinical observation of local surround acupuncture combined with ultrasound conductance drug penetration on chest wall tuberculosis
Objective To observe the efficacy of local surround acupuncture combined with ultrasound conductance drug penetration in the treatment of chest wall tuberculosis.Methods From August 2015 to August 2021,the patients were randomly assigned into a control group(n =78)and a treatment group(n = 83).All patients were managed by antituberculosis drugs combined with ultrasound conductance drug penetration(isoniazid,rifampin),and patients in the treatment group were addition-ally given local surround acupuncture.The efficacy was statistically analyzed after 2 months of treatment,aiming to compare in-flammatory indexes including serum C-reactive protein(CRP),erythrocyte sedimentation rate(ESR)and neutrophil count(NEU),and immune indexes(T lymphocyte subsets CD3+,CD4+,CD8+ and CD4+/CD8+).Results The cured and markedly effective rates of the treatment group were better than those in the control group(63.8%[53/83]vs 34.6%[27/78],P<0.05).After treatment,the levels of serum ESR,NEU and CRP in the treatment group were significantly lower(P<0.05),only the levels of serum ESR and CRP were significantly decreased in the control group(P<0.05).However,the levels of ESR,NEU and CRP in the treatment group were significantly lower than those in the control group(P<0.05).The levels of T lymphocyte subsets(CD3+,CD4+ and CD8+)in the two groups were significantly increased(P<0.05),and which were significantly higher in the treatment group than the control group(P<0.05),but there was no significant difference in the levels of CD4+/CD8+ between the two groups before and after treatment(P>0.05).Conclusion For chest wall tuberculosis,local surround acupuncture combined with ultrasound conductance drug penetration has a good effect,which can effectively promote the mass regression,inhibit the inflammatory reaction,improve the immune function of patients,and it is safe and reliable.

Chest wall tuberculosisUltrasound thera-pyAcupuncture therapy

李玲、陈志、王涛

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中国人民解放军总医院第八医学中心结核病医学部,北京 100091

结核 胸壁 超声疗法 针刺疗法

"十三五"艾滋病和病毒性肝炎等重大传染病防治国家科技重大专项

2018ZX10722-301-005

2024

河北中医
河北省医学情报研究所,河北省中医药学会

河北中医

CSTPCD
影响因子:0.951
ISSN:1002-2619
年,卷(期):2024.46(1)
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