首页|密集型银质针松解术联合中药熏洗治疗腰椎间盘突出症的临床研究

密集型银质针松解术联合中药熏洗治疗腰椎间盘突出症的临床研究

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目的 观察密集型银质针松解术联合中药熏洗治疗腰椎间盘突出症的临床疗效.方法 选择 2020 年 7月至2021 年7 月收治的腰椎间盘突出症患者104 例为本次研究对象,按照随机数字表法分为2 组,对照组52 例予中药熏洗治疗,治疗组52 例在对照组基础上联合密集型银质针松懈术治疗.2 组均治疗3 周后统计疗效,比较2 组治疗前后细胞因子血清基质金属蛋白酶3(MMP-3)、肿瘤坏死因子α(TNF-α)及转化生长因子-β1(TGF-β1)水平变化情况,比较2 组治疗前后疼痛视觉模拟评分(VAS)及日本骨科协会(JOA)评分变化情况,比较 2 组治疗前后腓总神经及胫神经运动传导速度变化情况.结果 治疗组总有效率94.23%(49/52),对照组总有效率80.77%(42/52),治疗组总有效率高于对照组(P<0.05).与本组治疗前比较,2 组治疗后细胞因子血清MMP-3、TNF-α及TGF-β1 水平均降低(P<0.05),且治疗组治疗后血清MMP-3、TNF-α及TGF-β1 水平均低于对照组(P<0.05).与本组治疗前比较,2组治疗后疼痛VAS均降低(P<0.05),JOA评分均升高(P<0.05),且治疗组治疗后疼痛VAS低于对照组(P<0.05),JOA评分高于对照组(P<0.05).与本组治疗前比较,2 组治疗后腓总神经及胫神经运动传导速度均增快(P<0.05),且治疗组治疗后腓总神经及胫神经运动传导速度快于对照组(P<0.05).结论 密集型银质针松解术结合中药熏洗治疗腰椎间盘突出症临床疗效确切,可有效缓解患者疼痛症状,提高腰椎功能,改善神经传导功能,其作用机制可能与降低MMP-3、TNF-α及TGF-β1 水平,减轻炎性,促进组织修复有关.
Effect of dense silver needle decompression combined with herbal fumigation in the treatment of lumbar disc herniation
Objective To explore the effect of dense silver needle decompression combined with herbal fumigation in the treatment of lumbar disc herniation(LDH).Methods A total of 104 patients with LDH who were treated in our hospital from July 2020 to July 2021 were randomly assigned into the control group(n =52)and the treatment group(n =52),all patients were treated with herbal fumigation,and patients in the treatment group were additionally treated with dense silver needle decom-pression.The treatment was performed for 3 weeks,aiming to compare the levels of serum matrix metalloproteinase-3(MMP-3),tumor necrosis factor-α(TNF-α)and transforming growth factor-β1(TGF-β1),as well as the scores of visual ana-logue scale(VAS)and Japanese Orthopaedic Association(JOA)between groups before and after treatment.The changes of mo-tor conduction velocity of common peroneal nerve(CPN)and tibial nerve(TN)before and after treatment were recorded between the two groups.Results The total effective rate in the treatment group was significantly higher than that of the control group(94.23%[49/52]vs 80.77%[42/52],P<0.05).After treatment,the levels of serum MMP-3,TNF-α and TGF-β1 in the two groups were significantly decreased(P<0.05),and the decrease was more obvious in the treatment group(P<0.05).Significantly decreased VAS scores(P<0.05)and significantly increased JOA scores(P<0.05)were detected in the both groups,and the treatment group was superior to the control group in VAS and JOA(all P<0.05).The motor conduction velocities of CPN and TN in the two groups increased significantly(P<0.05),and which in the treatment group were more faster than the control group(P<0.05).Conclusion For patients with LDH,dense silver needle decompression combined with herbal fumigation has a definite clinical effect,which can effectively relieve the pain symptoms of patients,improve lumbar func-tion and nerve conduction function by reducing the levels of MMP-3,TNF-α and TGF-β1,with reducing inflammation and promoting tissue repair.

Lumbar disc herniationDense silver needle decompressionHerbal fumigation

谌虎、沈浩

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四川省江油市第二人民医院疼痛康复医学科,四川 江油 621700

椎间盘突出,腰椎 密集型银质针松解术 中药熏洗

2024

河北中医
河北省医学情报研究所,河北省中医药学会

河北中医

CSTPCD
影响因子:0.951
ISSN:1002-2619
年,卷(期):2024.46(1)
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