Effect of integrated traditional Chinese and Western medicine on adverse reactions in patients with acute leukemia dur-ing chemotherapy
Objective To study the effect of integrated traditional Chinese and Western medicine on adverse reactions in patients with acute leukemia(AL)during chemotherapy.Methods A total of 80 AL patients undergoing chemotherapy admitted to our hospital from January 2020 to December 2022 were selected and randomly assigned into the control group and the treatment group,with 40 patients in each group,in which they received conventional Western medicine and integrated traditional Chinese and Western medicine,respectively.The constipation symptoms(nature of stool and difficulty of defecation)scores,36-item Short Form Health Survey(SF-36)(physiological function,physiological role,bodily pain,social function,vitality,emotional function,mental health,general health)scores,treatment satisfaction were compared.The dyssomnia and cancer-related fa-tigue(CRF)were assessed using Self-Rating Scale of Sleep(SRSS)and Piper Fatigue Scale,respectively.The mental status was assessed by Self-Rating Anxiety/Depression Scale(SAS/SDS).Results After treatment,the patients in the two groups presented significantly lower the scores of nature of stool and difficulty of defecation,SRSS and Piper Fatigue Scale,SAS/SDS(all P<0.05),and significantly higher the SF-36(physiological function,physiological role,bodily pain,social function,vi-tality,emotional function,mental health,general health)scores(P<0.05)than those before treatment,and the improvements were more pronounced in the treatment group than those of the control group(all P<0.05).The satisfaction in the treatment group was significantly higher than that in the control group([8.19±0.64]pointsvs[7.36±0.57]points,[P<0.05],respectively).Conclusion The integrated traditional Chinese and Western medicine can improve the symptoms of constipation,sleep disorders,and CRF in AL patients during chemotherapy,as well as improve their anxiety and depression symptoms,quality of life,and achieve high satisfaction.
LeukemiaChemotherapyIntegrated traditional Chinese and Western medicineDrug-related side effects and adverse reactions
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NSTL
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