Effect of combination therapy of traditional Chinese medicine on patients with post-stroke depression
Objective To analyze the effect of combination therapy of traditional Chinese medicine(TCM)on patients with post-stroke depression(PSD).Methods Sixty PSD patients treated in our hospital from March 2018 to March 2022 were randomly assigned into control group(n =30)and treatment group(n =30),in which they were treated with mirtazapine tablets and combination therapy of TCM,respectively.The treatment continued for 2 courses(1 course for 14 days).Before and after treatment,Hamilton Depression Rating Scale(HAMD)(including depression,obsessive-compulsive symptoms,sleep disor-ders,inferiority complex and paranoid symptoms),National Institutes of Health Stroke Scale(NIHSS)(including consciousness level,language barrier,visual field and facial paralysis),Activities of Daily Living Scale(ADL)(including clothing and eat-ing,bathing and dressing,stairs-climbing,walking,transfer bed chair)Postural Assessment Scale for Stroke(PASS)(including keep sitting without support,keep standing under support,keep standing without support,standing with unaffected lower limb,standing with paralyzed lower limb),Pittsburgh Sleep Quality Index(PSQI)(including sleep quality,sleep duration,sleep effi-ciency,daytime dysfunction and the use of hypnotic drugs)were included as comparators.Results After treatment,the dimen-sion scores of HAMD in the two groups lower significantly than those before treatment(P<0.05),the dimension scores and total scores of NIHSS in the two groups decreased significantly than those before treatment(P<0.05),the dimension scores of ADL in the two groups higher significantly than those before treatment(P<0.05),the dimension scores and total scores of PASS in the two groups increased significantly than those before treatment(P<0.05),the dimension scores and total scores of PSQI in the two groups decreased significantly than those before treatment(P<0.05),and the improvements were more pronounced in the treatment group relative to the control group(all P<0.05).Conclusion,Combination therapy of TCM for PSD patients has definite clinical efficacy,and which can effectively improve depression symptoms,promote neurological function repair,im-prove activity of daily living,postural control capacity,and sleep quality.
Stroke sequelaeDepressionAcupuncture therapyTraditional Chinese medicine therapyMassageAu-ricular point sticking
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